Results 51 to 60 of about 93,206 (296)

The Fate of SWCNTs in Mouse Peritoneal Macrophages: Exocytosis, Biodegradation, and Sustainable Retention

Frontiers in Bioengineering and Biotechnology, 2020
The understanding of toxicological and pharmacological profiles of nanomaterials is an important step for the development and clinical application of nanomedicines.
Ping-Xuan Dong, Ping-Xuan Dong, Xinfeng Song, Xinfeng Song, Jiwei Wu, Jiwei Wu, Shuqin Cui, Shuqin Cui, Guizhi Wang, Lianying Zhang, Hanwen Sun, Hanwen Sun   +11 more
doaj   +1 more source

Clinical characteristics of acute drug-induced dystonia in pediatric patients [PDF]

Clinical and Experimental Emergency Medicine, 2017
Objecstonia is a movement disorder in which muscles contract uncontrollably. Acute drug-induced dystonia (DID) can be diagnosed through detailed history taking and physical examination.
Hyun Woong Park, Jae Ryung Kwak, Ji Sook Lee   +2 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Mechanism of action of quercetin in regulating cellular autophagy in multiple organs of Goto-Kakizaki rats through the PI3K/Akt/mTOR pathway

Frontiers in Medicine
ObjectiveThis experimental study investigated the protective function of quercetin on the liver, spleen, and kidneys of Goto-Kakizaki (GK) rats and explores its mechanism of action on autophagy-related factors and pathways.Materials and methodsGK rats ...
Zhiqun Guo, Zhiqun Guo, Jingyu Zhang, Jingyu Zhang, Mianxin Li, Mianxin Li, Zengwei Xing, Zengwei Xing, Xi Li, Xi Li, Jiaqi Qing, Jiaqi Qing, Yuan Zhang, Yuan Zhang, Lemei Zhu, Lemei Zhu, Mingxu Qi, Xuemin Zou, Xuemin Zou   +18 more
doaj   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Corrections to “FastLeakyResNet-CIR: A Novel Deep Learning Framework for Breast Cancer Detection and Classification”

IEEE Access
Presents corrections to the paper, (Corrections to “FastLeakyResNet-CIR: A Novel Deep Learning Framework for Breast Cancer Detection and Classification”).
Ruiming Zeng, Boan Qu, Wei Liu, Jianghao Li, Hongshen Li, Pingping Bing, Shuangni Duan, Lemei Zhu   +7 more
doaj   +1 more source

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

FEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani, Hiroya Ueda, Ayumi Kawata, Yuki Sato, Kotomi Inomata, Hiroshi Mano, Masahiro Wada, Kenji Kobata   +7 more
wiley   +1 more source

Functional characteristics of fresh antitumor immune interferer GDF-15 in multiple cancers

Scientific Reports
We designed our study with the aim of conducting a comprehensive analysis of the role that GDF-15 plays in pan-cancer. Multiple databases were used to obtain GDF-15 expression.
Min Fang, Ziyu Wang, Yuxin Zhou, Fengrui Yang, Zhu Wu, Jian Xiao   +5 more
doaj   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source