Computational pharmaceutical materials science [PDF]
Pharmaceutical materials science addresses the physical solid-state properties of pharmaceutical products, such as solubility and stability of crystal structures. Especially the different properties of different polymorphs, salts and hydrates of an Active Pharmaceutical Ingredient (API) are of interest, although more recently the amorphous state has ...
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Dendrimer entrapped microsponge gel of dithranol for effective topical treatment
Dithranol is one of the important topical agents for the treatment of psoriasis, a chronic inflammatory skin disease with aberrant differentiation of keratinocytes.
Pushpendra Kumar Tripathi +4 more
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Effects of intermittent restriction diet and moderate-intensity exercise on the expression of cardiomyocytes in mice with high-glucose loads [PDF]
Context: The prevalence of obesity was 8% in 2002 and increased to 11.5% in 2011 in Indonesia. The results of the 2018 Basic Health Research stated that 13.6% of people over the age of 18 were overweight, and 21.8% were obese.
Eka Arum Cahyaning Putri +5 more
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The copper oxide nanoparticle has attracted increasing attention among all metal oxides due to its distinctive properties and applications. Chemical and physical methods of synthesizing copper oxide nanoparticles are challenged by high reagent costs ...
Hamed Mirhadi +2 more
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Enhanced anticancer effect of cetuximab combined with ethanol extract of Volvariella volvacea in colorectal cancer targeted TOP2A and PPARγ [PDF]
Context: Colorectal cancer (CRC) is a major global health concern as innovative therapeutic strategies to enhance treatment outcomes. This study investigates the therapeutic potential of the ethanol extract derived from Volvariella volvacea in ...
Sofy Permana +8 more
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Supramolecular Pharmaceutical Sciences: A Novel Concept for Future Pharmaceutical Sciences
Supramolecular chemistry is a useful and important domain for understanding pharmaceutical sciences, since various physiological reactions (e.g., protein association) and drug activities (e.g., the substrate/receptor reaction) are based on supramolecular chemistry. Biological components, such as DNA and cells, are also supermolecules.
Taishi, Higashi +2 more
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Multicomponent crystals: Solubility enhancement of simvastatin using arginine and glycine coformers [PDF]
Context: Simvastatin can be modified by the formation of multicomponent crystals to increase its solubility. Aims: To compare the solubility of multicomponent simvastatin crystals to pure simvastatin. Methods: The in silico study of simvastatin and
Iyan Sopyan +3 more
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Optimization of spray-drying conditions and quality assessment of dry extract from Perilla frutescens (L.) Britton leaves [PDF]
Context: Perilla frutescens and its dried extract have been employed in food and pharmaceutical manufacturing due to the plant's biological activities, which include antibacterial, anti-allergic, anticancer, antiviral, antioxidant, and antidepressant ...
Nguyen Thi Linh Tuyen +3 more
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Summary: Arthropod venoms contain bioactive molecules attractive for biomedical applications. However, few of these have been isolated, and only a tiny number has been characterized.
Pelin Erkoc +12 more
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Honey clinical applications in complementary medicine: A critical review [PDF]
Context: Honey has been employed for its therapeutic attributes since ancient eras, with a history of medicinal utilization, and recent studies have highlighted its diverse clinical applications. The medicinal benefits of honey can be ascribed to various
Thai Hau Koo +2 more
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