Results 41 to 50 of about 1,013,409 (346)

Recent advances in pharmaceutical sciences IV [PDF]

, 2014
Reproducció del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=234Like in the three previous editions, this E-book compiles a series of contributions in the multidisciplinary research arena of Pharmaceutical Sciences. The E-book has been
Estelrich i Latràs, Joan, Muñoz-Torrero López-Ibarra, Diego, Vázquez Carrera, Manuel   +2 more
core  

The Method of Forecasting of the Indicators for Drug Reimbursement to Patients with Cardiovascular Diseases in Ukraine [PDF]

, 2019
The aim of the study is to develop a method for forecasting the indicators for drug reimbursement to patients with cardiovascular diseases (CVD) in Ukraine within the framework of the government program “Available medicines”.Materials and methods ...
Kurylenko, Y. (Yuliia), Nazarkina, V. (Viktoriya), Nemchenko, A. (Alla)   +2 more
core   +3 more sources

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Professor Jalil Afshar; The Founding Editor of Pharmaceutical Sciences [PDF]

Pharmaceutical Sciences, 2022
Abolghasem Jouyban, Ali Shayanfar
doaj   +1 more source

Experience of and Attitudes toward Research among Pharmaceutical Sciences and PharmD Students in Saudi Arabia

Health Professions Education, 2019
Purpose: The aim of this study was to investigate attitudes toward, experience of, and perceived barriers to conducting research among Pharmaceutical Sciences and Doctor of Pharmacy (PharmD) students in pharmacy colleges in Saudi Arabia.
Rahaf Ali Alqahtani, Malak Abdulaziz Aldahash, Shahad Abdulsalam Alhulail, Mohammed Yahya Alzahrani, Lama Alfehaid, Hind Almodaimegh   +5 more
doaj   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

FEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello, Marcella Maringolo Cristovão, Guilherme Henrique, Vinicius Gonçalves Rodrigues, Caroline Serrano‐Nascimento, Edna Teruko Kimura, Cesar Seigi Fuziwara   +6 more
wiley   +1 more source

Special issue: Pharmaceutical innovation

Asian Journal of Pharmaceutical Sciences, 2018
“Pharmaceutical innovation” is an interdisciplinary area of the pharmaceutical sciences including drug development with a focus on manufacturing, process control, and technology, among many other subfields of research.
Pornsak Sriamornsak, Duangratana Shuwisitkul   +1 more
doaj   +1 more source

Transforming Pharmacy and Pharmaceutical Sciences Education in the Context of Workforce Development [PDF]

, 2017
KEY MESSAGES: 1.1 The continued development of pharmacy services and the pharmaceutical sciences relies on a well educated, competent, sufficient and well distributed pharmaceutical workforce. 1.2 There is no workforce without education.
Bader, L, Bates, I, Charman, W, Schneider, P   +3 more
core  

Experimental Pulmonary Granuloma Mimicking Sarcoidosis Induced by Propionibacterium acnes in Mice [PDF]

, 2010
Propionibacterium acnes has been implicated as an etiologic agent of sarcoidosis since the isolation of this bacterium from sarcoid lesions. We experimentally produced a murine pulmonary granuloma model using P.
Ichikawa, Hirohisa, Iio, Kouji, Iio, Tomoe Ueno, Kanehiro, Arihiko, Kataoka, Mikio, Miyahara, Nobuaki, Nakata, Yasunari, Okui, Yuhei, Tanimoto, Mitsune, Tanimoto, Yasushi   +9 more
core   +1 more source