Results 91 to 100 of about 224,413 (311)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Pharmacist working conditions [PDF]

Canadian Pharmacists Journal / Revue des Pharmaciens du Canada, 2016
I applaud the British Columbia College of Pharmacists for supporting an examination of pharmacist working conditions.1 This issue has been swept under the table for far too long, and it isn’t surprising to see that this study suggests that almost a third of pharmacists feel they are practising in an unsafe work environment. Almost 2 years ago, I had to
openaire   +2 more sources

Learning to prescribe - pharmacists' experiences of supplementary prescribing training in England [PDF]

, 2008
Background: The introduction of non-medical prescribing for professions such as pharmacy and nursing in recent years offers additional responsibilities and opportunities but attendant training issues.
A Elston, Allen Hutchinson, Anthony Avery, Centre for the Advancement of Inter-professional Education (CAIPE), Claire Anderson, D Dawoud, D Silverman, Department of Health, Department of Health, E Bradley, Elizabeth Murphy, F Lloyd, J George, Joanne Lymn, Julie Ratcliffe, L Emmerton, Louise Guillaume, M Offredy, M Tully, P Black, P Buckley, Paul Bissell, Paul Ward, R Jones, Richard J Cooper, RJ Cooper, RJ Cooper, Royal Pharmaceutical Society of Great Britain, Royal Pharmaceutical Society of Great Britain, S Morrison-Griffiths, S Warchal   +30 more
core   +8 more sources

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Pharmacists in Pharmacovigilance: Can Increased Diagnostic Opportunity in Community Settings Translate to Better Vigilance? [PDF]

, 2014
The pharmacy profession has undergone substantial change over the last two to three decades. Whilst medicine supply still remains a central function, pharmacist’s roles and responsibilities have become more clinic and patient focused.
AG Granas, AI Wertheimer, B Gray, C Gonzalez-Gonzalez, C Su, Christine Randall, Consumers’ Association, Consumers’ Association, Consumers’ Association, D Brown, D Stewart, David Brown, DM Ashcroft, E Horsley, E Kroger, E Richardson, G Marchildon, GD Lansam, JK Jesson, Justine Howard, K Grootheest van, KB Blake, L Emmerton, L Hanna, M Jadeja, M Rosenthal, M Tobaiqy, MA Hadi, MP Smith, N Black, N Iqbal, P Chan, P Gavaza, P Rutter, Paul Rutter, S Keyhani, SS Sardas, T Kimura, V Paudyal, Z Austin   +39 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

BREAST CANCER ASSISTANCE JOURNEY FROM THE PERSPECTIVE OF THE PUBLIC HEALTHCARE SERVICE OF RIO GRANDE DO SUL

Jornal de Assistência Farmacêutica e Farmacoeconomia
Objective: This study aims to characterize the breast cancer (BC) patient journey in Rio Grande do Sul (RS), Brazil, through the perspectives of the High Complexity Oncology Assistance Centers (CACONs) and High Complexity Oncology Assistance Units ...
Fernando Anschau, Sabrina Bedin, Luciane Kopittke, Tamie de Camargo Martins, Ruth Grigolon, Isabel Monteiro, Giovanna da Cunha Varolli, Rodrigo Luz   +7 more
doaj   +1 more source

A communication protocol between community pharmacists and primary care professionals to solve patients´ medication problems

International Journal of Integrated Care, 2019
Introduction: Communication between health professionals (HP) is a key issue to enhance quality and efficiency of health care system. (1,2). Community pharmacists (CPs) are often not integrated in the current HP communication model.
Ainhoa Oñatibia-Astibia, Belen Larrañaga, Josune Iribar, Arritxu Etxebarria, Nekane Odriozola, Miguel Ángel Gastelurrutia, Ana Bustinduy, Estibaliz Goyenechea   +7 more
doaj   +1 more source

Medical Marijuana and Pharmacy Practice [PDF]

, 2015
By way of the Compassionate Care Act of 2014, New York has become the 23rd state to create a process that will permit patients suffering from a “serious condition” to receive medical marijuana (or “cannabis”).
Williams, Karl G
core   +1 more source