Results 121 to 130 of about 323,198 (362)

Hospice Palliative Home Care in Canada: A Progress Report [PDF]

open access: yes, 2008
This report is a snapshot of hospice palliative home care services available to Canadians in 2008. The information refers only to hospice palliative care services provided in the home.
Jean Bacon
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Point-of-care testing of cardiovascular risk factors in Viennese community pharmacies: A cross-sectional study

open access: yesPreventive Medicine Reports
Objective: Despite being the leading contributor to global mortality, cardiovascular diseases remain undetected in many individuals at-risk. The aim of this study was to evaluate the proportion of individuals with unrecognised cardiovascular risk factors
Thorsten Bischof   +7 more
doaj   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

open access: yesFEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Voluntary information and price sharing database – a scoping review of the pricing and procurement landscape across eight Commonwealth Member States

open access: yesJournal of Pharmaceutical Policy and Practice
Background The Commonwealth Health Ministers’ meetings (2021–2023) identified medicines shortages, pricing, and price transparency as critical issues. This led to the establishment of the Voluntary Information and Price Sharing Database (VIPSD) in 2021 ...
Bridget Kebirungi   +11 more
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Psychometrics of the scale of attitudes toward physician-pharmacist collaboration: a study with medical students. [PDF]

open access: yes, 2012
BACKGROUND: Despite the emphasis placed on interdisciplinary education and interprofessional collaboration between physicians and pharmacologists, no psychometrically sound instrument is available to measure attitudes toward collaborative relationships ...
Fassihi, Reza   +5 more
core   +1 more source

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