Results 111 to 120 of about 162,217 (316)
Pharmacogenetics and the Pharmacy Profession: A Sociological Exploration [PDF]
, 2012 Pharmacy, particularly in the community setting, has been subject to significant changes over the last three decades. Running concurrently to these changes has been the development of the field of pharmacogenetics, or ‘personalised medicine’, which is ...
Jamie, Kimberly
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Skills for Pharmacists: A Patient-Focused Approach
, 2015 Skills for Pharmacists: a patient-focused approach explores current pharmacy practice and extends into skills for emerging practice areas.\ud \ud The fundamentals of patient-centred care are addressed including communication skills, ethics and evidence ...
Kyle, Greg +2 more
core
Tobacco cessation services by community pharmacists; a potential opportunity window
, 2018 Background Tobacco smoking has been proven to be addictive, and smokers would require some form of assistance to quit. Most smokers in Nigeria are unaware of cessation services nor have access to them.
Joshua Awogbemi +2 more
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
BMC Health Services ResearchBackground There is a growing need for community pharmacists to support universal health coverage by providing vaccination services to address low coverage, as they are among the most accessible healthcare professionals.
Adewale Aderemi Oladigbolu +3 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Pharmacists’ essential knowledge on cognitive impairment in the elderly population [PDF]
, 2017 Background: There are various factors which can lead to irreversible, reversible cognitive impairments. The progression of reversible cognitive disorders can be halted by identifying and treating the underlying cause.
Morrissey, Hana +2 more
core
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source