Results 151 to 160 of about 181,985 (340)

Pediatric Obesity: Influence on Drug Dosing and Therapeutics [PDF]

, 2018
Obesity is an ongoing global health concern and has only recently been recognized as a chronic disease of energy homeostasis and fuel partitioning. Obesity afflicts 17% of US children and adolescents.
Ameer, Barbara, PharmD, MBA, BCPS, FCP, Weintraub, Michael, MD   +1 more
core   +1 more source

Intelligent Theranostic Systems Enabled by Aggregation‐Induced Emission in Precision Medicine

Aggregate, EarlyView.
Aggregation‐induced emission (AIE) luminogens are driving a new generation of intelligent theranostic systems that integrate high‐fidelity imaging and multifunctional therapy. This review highlights how AIEgens, through restriction of intramolecular motion (RIM), enable deep‐tissue NIR‐II imaging, ultrasensitive biosensing, CRISPR‐assisted gene ...
Qinqin Huang, Yanyu Chen, Shile Wang, Kan Liu, Xing‐Zhong Zhao, Xiaobo Mao, Ben Zhong Tang, Lang Rao   +7 more
wiley   +1 more source

Biomimetic Thalidomide Nanoparticles: Targeted and Sustained Therapeutic Strategy for Oxygen‐Induced Retinopathy

Aggregate, EarlyView.
Magnesium acetyl taurate and thalidomide co‐assembled nanoparticles (MT NPs) are prepared via Super‐stable Pure Nanomedicine Formulation Technology (SPFT), and the NPs are further coated with transferrin‐modified cell membrane vesicles to construct Tfm@MT nanomedicine for oxygen‐induced retinopathy treatment.
Mengdie Li, Shundong Cai, Jinfa Ye, Lang Ke, Guanxiong Yang, Shaopan Wang, Cuiting Chen, Peixin Cai, Hui Liu, Xingyuan Wei, Songyi Wang, Yun Han, Shilong Shao, Min Su, Gang Liu, Chengchao Chu   +15 more
wiley   +1 more source

Beyond boundaries: Neuroprotective effects of steroids and ecdysteroids in SH‐SY5Y cells ‐ A systematic review

Neuroprotection
Steroids and ecdysteroids have been shown to exhibit a range of biological effects, including anti‐inflammatory, anticancer, and neuroprotective. This systematic review aims to highlight the evidence‐based neuroprotective and antioxidant effects of ...
Bizhar Ahmed Tayeb, Isaac Kinyua Njangiru, Renáta Minorics   +2 more
doaj   +1 more source

Pharmacokinetics and pharmacodynamics following single and repeated nightly administrations of loprazolam, a new benzodiazepine hypnotic. [PDF]

, 1985
GT McInnes, E. A. BUNTING, RM Ings, Joseph D. Robinson, SI Ankier   +4 more
openalex   +1 more source

Macrophage‐derived Extracellular Vesicles Disguised AIEgen/IDO1 Inhibitor Nanoplatform Reactivate “Immune‐Hot” for Photothermal Immunotherapy via Multi‐Dimensionally Reprograms Tumor Microenvironment

Aggregate, EarlyView.
Illustration of A/I@REHM nanoparticles preparation (A) and “ICB ‐ Repolarization ‐ PTT” like Poseidon's trident synergistically anti‐tumor treatment (B). ABSTRACT Reversing the tumor microenvironment (TME) from “cold” to “hot” tumor represents a pivotal strategy to overcome the clinical bottleneck of poor response rates to immunotherapy in solid tumors.
Xue Li, Xianglong Zhao, Yin Zhou, Yu Liu, Yushuo Feng, Yeneng Dai, Ping Gong, Qi Zhao, Ming Dong   +8 more
wiley   +1 more source

Oestrogen Receptor Alpha in Myocyte Maintains Muscle Regeneration in Duchenne Muscular Dystrophy

Journal of Cachexia, Sarcopenia and Muscle
Background Oestrogen receptor alpha (ERα) plays an important role in maintaining mitochondrial function and regulating metabolism in skeletal muscle.
Xiaofei Huang, Sijia Li, Huna Wang, Lei Zhao, Xihua Li, Shusheng Fan, Wanting Hu, Haowei Tong, Guangyao Guo, Dengqiu Xu, Luyong Zhang, Zhenzhou Jiang, Qinwei Yu   +12 more
doaj   +1 more source

Laboratory Manual of Pharmacology Including Materia Medica, Pharmacopaedics and Pharmacodynamics.

, 1920

openalex   +2 more sources

Pharmacokinetics and pharmacodynamics of verapamil in combination with atenolol, metoprolol and propranolol. [PDF]

, 1984
SJ Warrington, David Holt, A. E. Johnston, TJ Fitzsimons   +3 more
openalex   +1 more source

Pharmacokinetic principles [PDF]

, 2006
De Paepe, Peter, Kalmar, Alain, Struys, Michel   +2 more
core   +1 more source