Results 61 to 70 of about 36,199 (325)

Incidence in pharmacoepidemiology—Basic definitions and types of misclassification

Basic & Clinical Pharmacology & Toxicology, 2022
The definition of a new case is a vital step in incidence studies in both epidemiology and pharmacoepidemiology, although with significant differences in methodology between the fields. We define and apply a framework for two different types of new cases
M. Hoffmann, H. Støvring
semanticscholar   +1 more source

Use of depot medroxyprogesterone acetate and fracture risk [PDF]

, 2010
Depot medroxyprogesterone acetate (DMPA), which has a high rate of use among teenagers in Europe and the United States, has been associated with impaired bone mineral acquisition during adolescence and accelerated bone loss in later life.
Brauchli, Yolanda B., Jick, Susan S., Kraenzlin, Marius E., Meier, Christian, Meier, Christoph R.   +4 more
core   +1 more source

Linked health data for pharmacovigilance in children : Perceived legal and ethical issues for stakeholders and data guardians [PDF]

, 2014
Peer reviewedPublisher ...
Bond, Christine M, Francis, Jill J, Haughney, John, Helms, Peter J, Hopf, Yvonne Marina   +4 more
core   +2 more sources

Blood Pressure Control in the DIAbetes and LifEstyle Cohort Twente (DIALECT): The Role of Patient Adherence and Physician’s Follow-Up Action

Pharmacoepidemiology, 2023
We studied the role of adherence to antihypertensive drug therapy (AHT) in blood pressure (BP) control in a type 2 diabetes (T2D) population treated in secondary care in the DIAbetes and LifEstyle Cohort Twente-1 (DIALECT-1). In addition, intensification
Simone L. Dam, Heleen M. Masselink-Haverkate, Christina M. Gant, Stephan J. L. Bakker, Roos M. Nijboer, Willemien J. Kruik-Kollöffel, Gozewijn D. Laverman   +6 more
doaj   +1 more source

Pharmacoepidemiology of statins

Therapies, 2019
The evaluation of the real-life benefits and risks of statins in population is a major pharmacoepidemiological issue, given their widespread use for cardiovascular prevention. The purpose of this review was not to be exhaustive but to show the contributions of pharmacoepidemiology for various aspects of the evaluation of statins such as real-life drug ...
Julien Bezin, Nicholas Moore
openaire   +4 more sources

Methodological Considerations on the Use of Cohort Designs in Drug-Drug Interaction Studies in Pharmacoepidemiology

Current Epidemiology Reports
The evidence regarding the clinical effects of drug-drug interactions (DDIs) is scarce and limited. Pharmacoepidemiologic studies could help fill in this important knowledge gap. Here, we review the pharmacoepidemiology of DDIs with a focus on cohort
J. Dimakos, A. Douros
semanticscholar   +1 more source

Identifying Candidate Risk Factors for Prescription Drug Side Effects using Causal Contrast Set Mining [PDF]

, 2015
Big longitudinal observational databases present the opportunity to extract new knowledge in a cost effective manner. Unfortunately, the ability of these databases to be used for causal inference is limited due to the passive way in which the data are ...
Aickelin, Uwe, Guo, Zhaoyang, Reps, Jenna, Zhu, Haoyue   +3 more
core   +3 more sources

Analyzing Black Market Sales of the Second-Line ADHD Medication Atomoxetine

Pharmacoepidemiology, 2023
Research Question and Objective: While the number of pharmacoepidemiological studies on stimulant-based ADHD medications has expanded rapidly in recent years, likely due to the stimulant shortage, few studies have analyzed non-stimulant ADHD medications ...
Sophie A. Roe, Dayna S. DeSalve, Brian J. Piper   +2 more
doaj   +1 more source

Quasi-experimental methods for pharmacoepidemiology: difference-in-differences and synthetic control methods with case studies for vaccine evaluation

American Journal of Epidemiology
Difference-in-differences and synthetic control methods have become common study designs for evaluating the effects of changes in policies, including health policies.
L. Kennedy‐Shaffer
semanticscholar   +1 more source

Core concepts in pharmacoepidemiology: Violations of the positivity assumption in the causal analysis of observational data: Consequences and statistical approaches

Pharmacoepidemiology and Drug Safety, 2021
In the causal analysis of observational data, the positivity assumption requires that all treatments of interest be observed in every patient subgroup. Violations of this assumption are indicated by nonoverlap in the data in the sense that patients with ...
Yaqian Zhu, R. Hubbard, Jessica Chubak, J. Roy, N. Mitra   +4 more
semanticscholar   +1 more source