Results 201 to 210 of about 34,807 (281)

Correction: Blocking copper transporter protein-dependent drug efflux with albumin-encapsulated Pt(IV) for synergistically enhanced chemo-immunotherapy. [PDF]

J Nanobiotechnology
Fang M, Cao L, Zhang Z, Yu Z, Shen Y, Chen J, Chen J, Li YQ, Liu Z, Meng Y, Xiao H, Qu Q, Yin JY, Li XP.   +13 more
europepmc   +1 more source

Fruquintinib: Mechanism of Action, Clinical, and Translational Science

Clinical and Translational Science, Volume 19, Issue 10, October 2026.
ABSTRACT Fruquintinib is a highly selective, oral inhibitor of all three vascular endothelial growth factor receptors (‐1, ‐2, and ‐3) that was approved, including in China, the United States, and the European Union, for the treatment of previously treated metastatic colorectal cancer (mCRC).
Xiaofei Zhou, Arvind Dasari, Jin Li, Caly Chien, Qi Dong, Lucy Chen, Lixian Dong, Neeraj Gupta   +7 more
wiley   +1 more source

From Real World Data to Real Impact: A Co‐Medication Framework for Lung Cancer to Advance DDI Assessment and Patient‐Centric Drug Development

Clinical and Translational Science, Volume 19, Issue 10, October 2026.
ABSTRACT Lung cancer predominantly affects older adults who already experience comorbidities and are at increased risk of drug–drug interactions (DDIs) due to polypharmacy. Traditional DDI assessments often do not fully capture complex co‐medication patterns observed in real‐world practice due to the risk of introducing confounding factors.
Mareena Biju, HeeJae Choi, Shilpa Madari, Annie Carlisle, Ashish Sharma, Christina Kunz, Fenglei Huang   +6 more
wiley   +1 more source

Efficacy, Tolerability, and Safety of Fluoxetine for Panic Disorder in Adults: A Review. [PDF]

Cureus
Mohammad H, Singh S, Singh I.
europepmc   +1 more source

Paving the way for integrating genetic testing into clinical care in childhood‐onset schizophrenia

General Psychiatry, Volume 39, Issue 5, October 2026.
Arnaud Fernandez, Philippe Auby, Boris Chaumette, Gaelle Laure, Susanne Thümmler, Florence Askenazy   +5 more
wiley   +1 more source

PHARMWATCH: A Proposed Multilayer Pharmacogenomics Framework for Contextual Star Allele Interpretation

Clinical and Translational Science, Volume 19, Issue 10, October 2026.
ABSTRACT The Clinical Pharmacogenetics Implementation Consortium (CPIC) bases its drug‐gene recommendations on the assignment of star alleles, which map known genotypes to defined functional categories and corresponding drug dosage guidelines. The star allele framework, first proposed in 1996 for the CYP gene family and later formalized with CPIC's ...
Chris Eisenhart, Rachel Brickey, Joel Mewton   +2 more
wiley   +1 more source

Physiologically Based Pharmacokinetic (PBPK) Modeling of Antidepressants: A Scoping Review of Existing Models, Applications, and Software Tools. [PDF]

Clin Pharmacokinet
Huber RL, Scherf-Clavel O.
europepmc   +1 more source

Risk of Severe Hypoglycemia Associated With Concomitant Use of Sulfonylureas and Amiodarone

Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 9336-9345, October 2026.
ABSTRACT Aims To evaluate whether initiation of amiodarone while receiving sulfonylurea is associated with an increased risk of severe hypoglycemia compared with the initiation of other antiarrhythmic agents (flecainide, sotalol, or propafenone) while receiving sulfonylurea. Materials and Methods We conducted a population‐based cohort study using South
Sungho Bea, Hyesung Lee, Young Min Cho, You‐Jung Choi, Ju‐Young Shin, Katsiaryna Bykov   +5 more
wiley   +1 more source

Pharmacogenetics in Community Pharmacy: Global Perspectives and Implementation. [PDF]

J Clin Med
Rutkowska K, Chełstowska B, Religioni U, Borowska M, Kobayashi A, Vaillancourt R, Białoszewski A, Sikorski S, Doniec Z, Bromber P, Biala A, Kurek K, Pawlikowski J, Merks P.   +13 more
europepmc   +1 more source