Results 101 to 110 of about 78,276 (237)

Expanding Precompetitive Multisector Collaborations to Advance Drug Development and Pharmacogenomics. [PDF]

, 2020
Do, Thao P, Giacomini, Kathleen M, Huang, Shiew-Mei, Krauss, Ronald M, Kusuhara, Hiroyuki, Sugiyama, Yuichi, Unadkat, Jashvant D, Yee, Sook Wah   +7 more
core   +2 more sources

Pharmacogenomic Characterization in Bipolar Spectrum Disorders [PDF]

, 2019
Stefano Fortinguerra, Vincenzo Sorrenti, Pietro Giusti, Morena Zusso, Alessandro Buriani   +4 more
openalex   +1 more source

Identification of genetically predicted protein biomarkers and drug targets for prostate cancer via Mendelian randomization

VIEW, EarlyView.
Prostate cancer, a leading cause of cancer in men globally, urgently requires improved diagnostic and treatment strategies. This study analyzed large genetic datasets and identified five key proteins (THBD, DST, IFI27L2, OSBPL10, PPP1R14A) that either increase or decrease cancer risk, while also exploring their roles in immune response and potential ...
Maoping Cai, Tianming Peng, Zhiyue Xie, Chuqian Zhen, Chen Yao, Nan Peng, Qianyi Li, Yuzhong Yu, Jiming Bao, Xian‐Lu Song, Mingkun Chen, Shan‐Chao Zhao   +11 more
wiley   +1 more source

Knowledge, perceptions, and attitudes toward pharmacogenomics among pharmacists and pharmacy students: A systematic review

Health Science Reports
Background and Aims Pharmacists have been recognized as one of the most qualified healthcare professionals in the clinical implementation of pharmacogenomics, yet its widespread implementation in clinical pharmacy practice has remained limited.
Amanda Wondrasek, Amber Fryza, Md. Abdul Aziz, Christine Leong, Kaarina Kowalec, Abdullah Al Maruf   +5 more
doaj   +1 more source

Genetic polymorphisms analysis of pharmacogenomic VIP variants in Bai ethnic group from China [PDF]

, 2019
Wanlu Chen, Heng Ding, Yujing Cheng, Qi Li, Run Dai, Xin Yang, Chan Zhang   +6 more
openalex   +1 more source

Equal access to pharmacogenomics testing: The ethical imperative for population‐wide access in the UK NHS [PDF]

, 2023
Emma Magavern, Mark J. Caulfield
openalex   +1 more source

Pharmacogenetics of follicle‐stimulating hormone action in the male

Andrology, EarlyView.
Abstract Male factor infertility (MFI) is involved in half of the cases of couple infertility. The follicle‐stimulating hormone (FSH) therapy is considered efficient to improve semen parameters and pregnancy rate in patients with idiopathic MFI, following the lesson learned from hypogonadotropic hypogonadism.
Andrea Graziani, Giuseppe Grande, Raffele Scafa, Riccardo Selice, Andrea Garolla, Maria Santa Rocca, Cinzia Vinanzi, Alberto Ferlin   +7 more
wiley   +1 more source

Pharmacogenetics and pharmacogenomics: The impact of the single nucleotide polymorphisms in drug response [PDF]

, 2015
Ivan Jančić, Nevena Arsenović-Ranin
openalex   +1 more source

Targeting hexokinase 2 to induce breast cancer cell senescence

British Journal of Pharmacology, EarlyView.
Background and Purpose Hexokinase 2 (HK2) is a key enzyme linked to high tumour cell proliferation. Its inhibitors such as 3‐bromopyruvic acid (3‐BP) induce cancer cell death, highlighting HK2 modulation as potential anti‐cancer treatment. However, standard chemotherapies often cause the emergence of senescent cancer cells, which goes along with cell ...
Helmut Bischof, Katarina Cisarova, Sandra Burgstaller, Mia Schwerer, Markus Absenger‐Novak, Philipp J. Jost, Roland Malli, Wolfgang F. Graier, Robert Lukowski   +8 more
wiley   +1 more source

PharmacoDB 2.0 : Improving scalability and transparency of in vitro pharmacogenomics analysis [PDF]

, 2021
Nikta Feizi, Sisira Kadambat Nair, Petr Smirnov, Gangesh Beri, Christopher Eeles, Parinaz Nasr Esfahani, Minoru Nakano, Denis Tkachuk, Anthony Mammoliti, Evgeniya Gorobets, Arvind Singh Mer, Eva Lin, Yihong Yu, Scott E. Martin, Marc Hafner, Benjamin Haibe‐Kains   +15 more
openalex   +1 more source