Results 111 to 120 of about 39,211 (299)

Nudix hydrolase 15 deficiency and azathioprine toxicity in a liver transplant recipient: A case report

open access: yesJPGN Reports, EarlyView.
Abstract Thiopurines, such as azathioprine (AZA), are among the immunosuppressants used to prevent allograft rejection. Thiopurines are metabolized by thiopurine S‐methyltransferase (TPMT) and nudix hydrolase 15 (NUDT15) enzymes, and their functions are highly influenced by genetic variation. We present a 6‐year‐old female with recurrent acute cellular
Jenny Q. Nguyen   +4 more
wiley   +1 more source

Pharmacogenomics: today, tomorrow and beyond

open access: yes, 1999
Pharmacogenomics is today’s hot topic in biotechnology. In 1996 the word did not even exist; now international pharmacogenomics meetings are held monthly, and articles appear weekly in scientific journals ind the popular press. In this Viewpoint article,
Bhagat, K.
core  

Pharmacogenomics and personalized medicine in clinical practice

open access: yes, 2011
The Santorini Conference on prospective biology, genomics and pharmacogenomics occurs every 2 years. On 30 September to 2nd October 2010, the fifth meeting in this series took place in Santorini, Greece.
Dechairo, B   +26 more
core   +1 more source

Artificial Intelligence in Dermatology: Current Applications and Future Directions

open access: yesJEADV Clinical Practice, EarlyView.
This scoping review of 56 studies maps AI applications in dermatology. Image‐based classification for skin cancer detection dominates (48%), followed by clinical decision support (21%), teledermatology triage (11%), and predictive analytics (11%). While deep learning algorithms demonstrate diagnostic performance comparable to clinicians in controlled ...
Sofía Pérez‐Lalinde   +1 more
wiley   +1 more source

The pharmacogenomics of pain management: prospects for personalized medicine

open access: yes, 2016
Sonya Ting,1 Stephan Schug2,3 1Department of Anaesthesia, Sir Charles Gairdner Hospital, Perth, WA, Australia; 2Anaesthesiology Unit, School of Medicine and Pharmacology, University of Western Australia, Perth, WA, Australia; 3Department of Anaesthesia ...
Ting S, Schug S
core  

Exploring the Reproductive Toxicity of Bisphenol S Through a Network Toxicology and Molecular Docking Analysis

open access: yesPediatric Discovery, EarlyView.
Utilizing network toxicology, molecular docking, and dynamic simulations to investigate the potential reproductive toxicity of bisphenol S (BPS). ABSTRACT The aim of this study was to investigate the potential reproductive toxicity of bisphenol S (BPS) and the related molecular mechanisms through a network toxicology approach.
Siyuan Wang   +7 more
wiley   +1 more source

PHARMACOGENOMICS AND PERSONALIZED MEDICINE

open access: yes
Pharmacogenomics, which examines the role of genetic variability in drug responses, is one of the pillars of precision medicine. The phenomenon of interindividual differences in drug metabolism, pharmacodynamics and therapeutic results is increasingly ...
Jya Tomar, Ravindra Mishra,
core   +1 more source

The pharmacogenomics of depression [PDF]

open access: yesThe Pharmacogenomics Journal, 2001
J, Licinio, M L, Wong
openaire   +2 more sources

Introducing lifestyle medicine residency curriculum into PM&R residency training: Implementation experience and early benefits

open access: yesPM&R, EarlyView.
Abstract Background Lifestyle medicine (LM) aligns closely with physical medicine and rehabilitation (PM&R), emphasizing holistic, patient‐centered approaches to optimize health and function. Despite this synergy, structured LM education within PM&R residencies remains limited.
Matison Alderman   +3 more
wiley   +1 more source

From prediction to intervention: Causal artificial intelligence as the missing link in precision therapeutics

open access: yesPrecision Medical Sciences, EarlyView.
Predictive multiomics artificial intelligence (AI) identifies risk but does not indicate which intervention will change a patient's outcome; causal AI, anchored in biological mechanism, bridges this gap to enable individualized treatment decisions.
Gedion Mengistu Dejen
wiley   +1 more source

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