Results 101 to 110 of about 39,211 (299)
Pharmacogenomics of Open-Angle Glaucoma
Pharmacogenomics of Open-Angle ...
Schwartz, Stephen G
core +3 more sources
Pharmacogenomics in osteoporosis: Steps toward personalized medicine
Robert Greene1, Shaymaa S Mousa, Mohamed Ardawi2, Mohamed Qari2, Shaker A Mousa11The Pharmaceutical Research Institute, Albany College of Pharmacy and Health Sciences, Albany, NY, USA; 2Center of Excellence in Osteoporosis Research, King Abdul Aziz ...
Mohamed Ardawi +3 more
core
Pharmacogenomics (PGx) has emerged as an encouraging tool in chronic pain therapy. Genetic variations associated with drug effectiveness or adverse reactions (amitriptyline/nortriptyline/codeine/oxycodone/tramadol-CYP2D6, amitriptyline-CYP2C19 ...
De Moraes, Natália Valadares [UNESP] +3 more
core +1 more source
Natural products and traditional Chinese medicine target metabolic pathways underlying right ventricular dysfunction in pulmonary arterial hypertension. Integrating multi‐omics, artificial intelligence, and systems biology may enable precision cardiometabolic therapies to restore right ventricular metabolism and improve clinical outcomes.
Yihao Wu, Zhehui Tang, Hongwei Yao
wiley +1 more source
KLF15 as a Metabolic Gatekeeper Linking Drug Metabolism, Toxicity, and Precision Therapeutics
KLF15‐mediated metabolic preconditioning links metabolic state to drug disposition, therapeutic efficacy, and adverse effects, extending classical xenobiotic sensing toward precision pharmacology. ABSTRACT Krüppel‐like factor 15 (KLF15) is emerging as a metabolic‐state‐sensitive regulator of hepatic endobiotic and xenobiotic metabolism.
Shilin Li +3 more
wiley +1 more source
Genetics in Dental Education: A Cross‐Sectional Study of Instruction and Clinical Integration
ABSTRACT Purpose Advances in genomic science and biomedical technology have positioned dentists as key contributors to evidence‐based care, including recognizing oral and craniofacial conditions that may warrant referral or interprofessional evaluation.
Tiffany Saba +5 more
wiley +1 more source
Patient responses to the drugs are highly influential by their genes, called pharmacogenomics, therefore, gene personalized therapy regulating more efficiently the side effects and drug efficacy, individually. For the coupling of pharmacogenomics to the
BUSHRA HINA, SAMAN USMANI, KIRAN RAFIQ
doaj
There is great variation in drug-response phenotypes, and a "one size fits all" paradigm for drug delivery is flawed. Pharmacogenomics is the study of how human genetic information impacts drug response, and it aims to improve efficacy and reduced side ...
Konrad J Karczewski +3 more
doaj +1 more source
Pharmacogenomics: today, tomorrow and beyond
Pharmacogenomics is today’s hot topic in biotechnology. In 1996 the word did not even exist; now international pharmacogenomics meetings are held monthly, and articles appear weekly in scientific journals ind the popular press. In this Viewpoint article,
Bhagat, K.
core
Pharmacogenomics: what is next? [PDF]
Pharmacogenomics is moving from a candidate gene strategy to large scale approaches. This is in line with the new paradigm of linking a trait to (a) pathway(s) rather than to single genes.
Julia edi Iulio +6 more
core +1 more source

