Results 101 to 110 of about 39,211 (299)

Pharmacogenomics of Open-Angle Glaucoma

open access: yes, 2011
Pharmacogenomics of Open-Angle ...
Schwartz, Stephen G
core   +3 more sources

Pharmacogenomics in osteoporosis: Steps toward personalized medicine

open access: yes, 2009
Robert Greene1, Shaymaa S Mousa, Mohamed Ardawi2, Mohamed Qari2, Shaker A Mousa11The Pharmaceutical Research Institute, Albany College of Pharmacy and Health Sciences, Albany, NY, USA; 2Center of Excellence in Osteoporosis Research, King Abdul Aziz ...
Mohamed Ardawi   +3 more
core  

Pharmacogenomics in chronic pain therapy: From disease to treatment and challenges for clinical practice

open access: yes, 2019
Pharmacogenomics (PGx) has emerged as an encouraging tool in chronic pain therapy. Genetic variations associated with drug effectiveness or adverse reactions (amitriptyline/nortriptyline/codeine/oxycodone/tramadol-CYP2D6, amitriptyline-CYP2C19 ...
De Moraes, Natália Valadares [UNESP]   +3 more
core   +1 more source

Traditional Chinese Medicine and Natural Products Targeting Right Ventricular Dysfunction in Pulmonary Arterial Hypertension: Toward Precision Cardiometabolic Therapy

open access: yesiNew Medicine, EarlyView.
Natural products and traditional Chinese medicine target metabolic pathways underlying right ventricular dysfunction in pulmonary arterial hypertension. Integrating multi‐omics, artificial intelligence, and systems biology may enable precision cardiometabolic therapies to restore right ventricular metabolism and improve clinical outcomes.
Yihao Wu, Zhehui Tang, Hongwei Yao
wiley   +1 more source

KLF15 as a Metabolic Gatekeeper Linking Drug Metabolism, Toxicity, and Precision Therapeutics

open access: yesiNew Medicine, EarlyView.
KLF15‐mediated metabolic preconditioning links metabolic state to drug disposition, therapeutic efficacy, and adverse effects, extending classical xenobiotic sensing toward precision pharmacology. ABSTRACT Krüppel‐like factor 15 (KLF15) is emerging as a metabolic‐state‐sensitive regulator of hepatic endobiotic and xenobiotic metabolism.
Shilin Li   +3 more
wiley   +1 more source

Genetics in Dental Education: A Cross‐Sectional Study of Instruction and Clinical Integration

open access: yesJournal of Dental Education, EarlyView.
ABSTRACT Purpose Advances in genomic science and biomedical technology have positioned dentists as key contributors to evidence‐based care, including recognizing oral and craniofacial conditions that may warrant referral or interprofessional evaluation.
Tiffany Saba   +5 more
wiley   +1 more source

DEMOGRAPHIC SURVEY REGARDING PERCEPTION AND IMPLEMENTATION OF PHARMACOGENOMICS AMONG GRADUATING PHARMACIST AND PROFESSIONALS IN KARACHI, PAKISTAN

open access: yesFUUAST Journal of Biology
Patient responses to the drugs are highly influential by their genes, called pharmacogenomics, therefore, gene personalized therapy regulating more efficiently the side effects and drug efficacy, individually. For the coupling of pharmacogenomics to the
BUSHRA HINA, SAMAN USMANI, KIRAN RAFIQ
doaj  

Chapter 7: Pharmacogenomics.

open access: yesPLoS Computational Biology, 2012
There is great variation in drug-response phenotypes, and a "one size fits all" paradigm for drug delivery is flawed. Pharmacogenomics is the study of how human genetic information impacts drug response, and it aims to improve efficacy and reduced side ...
Konrad J Karczewski   +3 more
doaj   +1 more source

Pharmacogenomics: today, tomorrow and beyond

open access: yes, 2019
Pharmacogenomics is today’s hot topic in biotechnology. In 1996 the word did not even exist; now international pharmacogenomics meetings are held monthly, and articles appear weekly in scientific journals ind the popular press. In this Viewpoint article,
Bhagat, K.
core  

Pharmacogenomics: what is next? [PDF]

open access: yes, 2011
Pharmacogenomics is moving from a candidate gene strategy to large scale approaches. This is in line with the new paradigm of linking a trait to (a) pathway(s) rather than to single genes.
Julia edi Iulio   +6 more
core   +1 more source

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