Results 131 to 140 of about 67,526 (234)

Cardiovascular‐Kidney‐Metabolic Syndrome in People With HIV: An Emerging Frontier for Clinical Pharmacology

Clinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1136-1140, May 2026.
As antiretroviral therapy (ART) prolongs lifespans, people with HIV (PWH) face a new syndemic: Cardiovascular‐Kidney‐Metabolic (CKM) syndrome. Yet CKM in PWH is poorly characterized. Inflammation, complex pharmacokinetic (PK) alterations, ART‐associated metabolic effects, and gut dysbiosis amplify risk. Managing CKM increases medication burden, thereby
Aaron S. Devanathan, Thomas D. Nolin
wiley   +1 more source

At the Right Time: Temporal Precision in Personalised Medicine

Sociology of Health &Illness, Volume 48, Issue 4, May 2026.
ABSTRACT Personalised medicine was initially heralded as delivering ‘the right drug to the right patient at the right time’. Although molecular precision has dominated recent developments, the temporal dimension has remained underexplored. This paper examines how temporal precision is emerging as a defining feature of next‐generation precision medicine,
Dominik Hofmann, Elena Esposito
wiley   +1 more source

Molecular Biology at the bedside: the impact of Genomics on the practice of medicine [PDF]

, 2002
Imagine being a newborn baby, discharged home after delivery, with a most unusual gift, a compact disc (CD) carrying all data on "My Genome". The parents would be most anxious to play it on their home PC. Soon, they could discover whether their child has
Felice, Alex
core  

Pharmacogenetics of follicle‐stimulating hormone action in the male

Andrology, Volume 14, Issue 4, Page 1064-1072, May 2026.
Abstract Male factor infertility (MFI) is involved in half of the cases of couple infertility. The follicle‐stimulating hormone (FSH) therapy is considered efficient to improve semen parameters and pregnancy rate in patients with idiopathic MFI, following the lesson learned from hypogonadotropic hypogonadism.
Andrea Graziani, Giuseppe Grande, Raffele Scafa, Riccardo Selice, Andrea Garolla, Maria Santa Rocca, Cinzia Vinanzi, Alberto Ferlin   +7 more
wiley   +1 more source

Mechanisms of organotropism in breast cancer and predicting metastasis to distant organs using deep learning

Discover Oncology
Background Metastasis, the spread of cancer cells from the primary tumor to distant organs, is the leading cause of mortality in cancer patients. This process often exhibits a preference for specific organs, a phenomenon known as tumor organotropism ...
Meizhu Xiao, Zhijin Fu, Yanjiao Li, Min Zhang, Denan Zhang, Lei Liu, Qing Jin, Xiujie Chen, Hongbo Xie   +8 more
doaj   +1 more source

How Has the Rise of Direct‐To‐Consumer Genetic Testing Impacted Genetic Counselling Practice? A Scoping Review

Clinical Genetics, Volume 109, Issue 5, Page 819-836, May 2026.
This scoping review consolidated research on genetic health practitioners' (GHPs) and direct to consumer genetic testing (DTC‐GT) consumer needs and identified gaps. Thematic analysis identified four domains: GHPs' views, GHPs' perceptions of the impact of DTC‐GT on consumers, how DTC‐GT impacted services and how DTC‐GT impacted roles.
Cushla McKinney, Giselle Newton, Vaishnavi Nathan, Aideen McInerney‐Leo   +3 more
wiley   +1 more source

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, Volume 73, Issue 4, April 2026.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source

Investigation of community pharmacists’ knowledge and attitudes of pharmacogenomics testing: implication for improved pharmacogenomic testing practice

Human Genomics
Background Community pharmacists must be well-equipped to advance pharmacogenomics services. Nevertheless, limited data is available regarding pharmacists' knowledge and attitudes toward pharmacogenomics testing.
Azza Ramadan, Anan S. Jarab, Ahmad Z. Al Meslamani   +2 more
doaj   +1 more source

Cancer pharmacogenomics, challenges in implementation, and patient-focused perspectives

Pharmacogenomics and Personalized Medicine, 2016
Jai N Patel Department of Cancer Pharmacology, Levine Cancer Institute, Carolinas HealthCare System, Charlotte, NC, USA Abstract: Cancer pharmacogenomics is an evolving landscape and has the potential to significantly impact cancer care and precision ...
Patel JN
doaj  

Carcinogenic Medications: A Review of Specific Agents and Molecular Mechanisms of Carcinogenesis

Cancer Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background Pharmacovigilance has revealed an alarming correlation between certain medications and a higher risk of cancer. In this narrative review, included research from 2020 to 2025, along with a few seminal older studies, so that it provides a clear picture of which drugs actually set off cancer and mechanisms involved at the molecular ...
Desta Seyoum Tadesse, Kalkidan Tekletsadik, Berhan Begashaw, Awgichew Shewasinad Yehualashet, Awol Mekonnen Ali, Kassahun Dires Ayenew   +5 more
wiley   +1 more source