Results 231 to 240 of about 38,200 (304)

Effectiveness of pharmacogenomics-guided dosing in improving treatment outcomes. [PDF]

Indian J Pharmacol
Karthikeyan LV, Subamathi A, Pragathi P, Vaishnavi S, Sanjana V, Sangamithra R.   +5 more
europepmc   +1 more source

A SHAP‐Informed Formal Feature Attribution Framework for Drug–Drug Interaction Risk in Large‐Scale Claims Data

Clinical and Translational Science, Volume 19, Issue 9, September 2026.
ABSTRACT Pairwise drug–drug interaction databases flag co‐prescribed pairs, but they under‐weight multi‐drug combinations that drive adverse drug events in older adults. We studied that gap in Virginia All‐Payer Claims Database records (2016–2019) for adults aged 65–114 years with non‐opioid emergency department visits (n = 1182 cases; 16,105 matched ...
R. Jerome Dixon, Elvin T. Price
wiley   +1 more source

Integrating genomic medicine into primary care: a precision health model from Riyadh, Saudi Arabia. [PDF]

Fam Med Community Health
Alabduljabbar K, Alaskar A, Al Alshaykh H, Alzaidan H, Alanazi S, Massart M.   +5 more
europepmc   +1 more source

Dolutegravir population pharmacokinetics in racially, sex‐ and age‐diverse and antiretroviral therapy‐experienced adults with HIV in the United States

HIV Medicine, Volume 27, Issue 9, Page 1517-1529, September 2026.
Abstract Objectives Dolutegravir (DTG) has been associated with weight gain in women with HIV, Black people with HIV and people with HIV60 years. This study aimed to characterise DTG population pharmacokinetics (PopPK) in a diverse population including these sub‐populations.
Adrian Khoei, Andrew Edmonds, Yen Chang, Catalina Ramirez, Mackenzie Vogan, Amanda Poliseno, Steven Wolinsky, Ken Ho, Todd T. Brown, Joseph B. Margolick, Jacquett Batson, Jennifer Hoffmann, Mark A. Marzinke, Mirjam‐Colette Kempf, Maria L. Alcaide, Joffi Effoe, Cecile D. Lahiri, Igho Ofotokun, Anandi N. Sheth, Stephen Gange, Audrey L. French, Bani Tamraz, Bradley E. Aouizerat, Phyllis C. Tien, Seble G. Kassaye, Jack DeHovitz, Kathryn Anastos, Kara W. Chew, Michelle Floris‐Moore, Julie B. Dumond   +29 more
wiley   +1 more source

Bridging the Gap Between Pharmacogenomic Discovery and Clinical Implementation: Insights from Selected Studies on Inter-Individual Variability in Drug Response. [PDF]

J Pers Med
Lee SJ.
europepmc   +1 more source

Cancer‐Control Outcomes of Japanese Vs. German Metastatic Hormone‐Sensitive Prostate Cancer Patients: A Real‐World Cross‐Country Comparison of Patients Undergoing Combination Therapies

International Journal of Urology, Volume 33, Issue 9, September 2026.
ABSTRACT Objectives Differences in tumor biology, ethnicities, and healthcare structures across populations may contribute to variability in oncologic outcomes. This study compared baseline characteristics and oncologic outcomes of Japanese and German metastatic hormone‐sensitive prostate cancer (mHSPC) patients.
Mike Wenzel, Keiichiro Miyajima, Maximilian Filzmayer, Axel S. Merseburger, Carolin Siech, Benedikt Lauer, Felix K.‐H. Chun, Shin Koike, Yoichiro Tohi, Takafumi Yanagisawa, Kojiro Tashiro, Takahiro Kimura, Fumihiko Urabe, Philipp Mandel   +13 more
wiley   +1 more source

Managing Secondary Findings from Germline Pharmacogenomic Testing. [PDF]

J Pers Med
Lee YM, Kearney E, Kisor DF, Farrell CL.
europepmc   +1 more source

Health Service Delivery Outcomes From Nursing in Genomics: A Scoping Review of the Literature (2012–2025)

International Nursing Review, Volume 73, Issue 3, September 2026.
ABSTRACT Aim This study aimed to summarize the current state of the science for “health service delivery–oriented outcomes” from nursing in genomics (2012–2025). Background Nurses can play a vital role in increasing access to genomic healthcare and improving outcomes for patients, families, and communities.
Jordan N. Keels, Joanne Thomas, Kathleen A. Calzone, Laurie Badzek, Sarah Dewell, Emma T. Tonkin, Andrew A. Dwyer   +6 more
wiley   +1 more source

Cardiologists' perspectives on pharmacogenomics implementation in a hybrid health system: A qualitative study from the United Arab Emirates. [PDF]

PLoS One
Abbas MO, Rahma AT, Elbarazi I, Ali BR, Patrinos GP, Ghadibah H, Al Muaini A, Al-Maskari F.   +7 more
europepmc   +1 more source

Boy in the Barrel: Excruciating Paroxysmal Pain Disorder Associated With an SCN9A Gain‐of‐Function Variant

Journal of the Peripheral Nervous System, Volume 31, Issue 3, September 2026.
ABSTRACT Background and Aims Gain‐of‐function variants in SCN9A, encoding the Nav1.7 sodium channel, cause inherited painful neuropathic disorders. We report a young man with severe childhood‐onset heat‐triggered paroxysmal pain, autonomic dysfunction, skeletal abnormalities, and a de novo SCN9A p.Ile234Thr variant, emphasizing the diagnostic and ...
Pedro Jose Tomaselli, Rodrigo Siqueira Soares Frezatti, Christopher J. Record, Maria Cristina Lopes Schiavoni, Natalia Dominik, Jana Vandrovcova, Mary M. Reilly, Wilson Marques Jr   +7 more
wiley   +1 more source