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A functional ancestry-linked regulatory haplotype influences CYP2D6 expression. [PDF]
Pharmacogenomics JMcCoy M.
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Pharmacogenomics to Improve Supportive Care Symptoms. A Prospective Observational Study Protocol
Patel M +3 more
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Current Drug Metabolism, 2008
Pharmacogenetics is the intersection of the fields of pharmacology and genetics. Simply stated, pharmacogenetics is the study of how genetic variations affect the ways in which people respond to drugs. These variations can manifest themselves as differences in the drug targets or as differences in the enzymes that metabolize drugs.
Virendra S, Gomase +3 more
+7 more sources
Pharmacogenetics is the intersection of the fields of pharmacology and genetics. Simply stated, pharmacogenetics is the study of how genetic variations affect the ways in which people respond to drugs. These variations can manifest themselves as differences in the drug targets or as differences in the enzymes that metabolize drugs.
Virendra S, Gomase +3 more
+7 more sources
Nihon rinsho. Japanese journal of clinical medicine, 2009
Pharmacogenomics encompasses several major areas including the identification and analysis of variations of DNA and RNA that affect the efficacy and toxicity of drug therapy. It represents an integration of analytical approaches including DNA and RNA detection and quantitation which may be applied to either candidate genes or a global genome analysis.
Shilong, Zhong, Marjorie, Romkes
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Pharmacogenomics encompasses several major areas including the identification and analysis of variations of DNA and RNA that affect the efficacy and toxicity of drug therapy. It represents an integration of analytical approaches including DNA and RNA detection and quantitation which may be applied to either candidate genes or a global genome analysis.
Shilong, Zhong, Marjorie, Romkes
+7 more sources
Nursing Clinics of North America, 2000
The completion of the Human Genome Project is expected by the year 2003. This mapping of standard human gene sequences and common variants will provide a reference database. This information will also provide new areas of research and study. An example of this is pharmacogenomics, an area of research and development that studies the genetically ...
B F, Persing, D J, Cheek
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The completion of the Human Genome Project is expected by the year 2003. This mapping of standard human gene sequences and common variants will provide a reference database. This information will also provide new areas of research and study. An example of this is pharmacogenomics, an area of research and development that studies the genetically ...
B F, Persing, D J, Cheek
openaire +2 more sources
Advances in Anatomic Pathology, 2004
The discovery of the human genome and subsequent expansion of proteomics research combined with emerging technologies such as functional imaging, biosensors and sophisticated computational biology are producing unprecedented changes in today's healthcare. The expanding knowledge of the molecular basis of cancer has shown that significant differences in
Jeffrey S, Ross +7 more
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The discovery of the human genome and subsequent expansion of proteomics research combined with emerging technologies such as functional imaging, biosensors and sophisticated computational biology are producing unprecedented changes in today's healthcare. The expanding knowledge of the molecular basis of cancer has shown that significant differences in
Jeffrey S, Ross +7 more
openaire +2 more sources
2005
So far no pharmacogenetic/genomic study has been conducted specifically for anxiety disorders. Some of the presented results, however, do pertain to such disorders. For example, pharmacokinetic aspects of antidepressant drug therapy likely also apply to patients with anxiety disorders, and several genetic polymorphisms in the cytochrome P450 (CYP) gene
Binder, E., Holsboer, F.
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So far no pharmacogenetic/genomic study has been conducted specifically for anxiety disorders. Some of the presented results, however, do pertain to such disorders. For example, pharmacokinetic aspects of antidepressant drug therapy likely also apply to patients with anxiety disorders, and several genetic polymorphisms in the cytochrome P450 (CYP) gene
Binder, E., Holsboer, F.
openaire +4 more sources
Expert Opinion on Pharmacotherapy, 2009
Circulatory disease accounts for fifteen million deaths each year, of which stroke accounts for four and a half million- with an estimated nine million stroke survivors annually. The overall incidence rate of stroke is 2 to 2.5 per thousand adults with an approximate prevalence of 5 per thousand and an estimated 5-year risk of stroke recurrence of 15 ...
Billeci AM +2 more
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Circulatory disease accounts for fifteen million deaths each year, of which stroke accounts for four and a half million- with an estimated nine million stroke survivors annually. The overall incidence rate of stroke is 2 to 2.5 per thousand adults with an approximate prevalence of 5 per thousand and an estimated 5-year risk of stroke recurrence of 15 ...
Billeci AM +2 more
openaire +3 more sources