Four Decades of Cytochrome P450 Research in Africa: A Historical Overview of Scientific Contributions, Research Trends, and Future Directions. [PDF]
Syed K.
europepmc +1 more source
ABSTRACT Background and Aims Doxorubicin‐cyclophosphamide (AC) chemotherapy induces hepatotoxicity through oxidative stress and inflammatory pathway activation, but prospective African data are lacking and conventional liver tests may miss subclinical injury.
Tamrat Nida, Abdisa Tufa Bedada
wiley +1 more source
ABSTRACT Background Anti‐tuberculosis drug‐induced liver injury (ATDILI) is one of the most prevalent and serious adverse reactions during anti‐tuberculosis treatment and can potentially lead to liver failure or mortality. This study aims to investigate whether genetic variants in the N‐acetyltransferase 2 gene (NAT2) and the HLA‐DOA gene (HLA‐DOA) are
Zhenzhen Zhao +6 more
wiley +1 more source
Public awareness, attitudes, and concerns regarding pharmacogenomics in the Kingdom of Saudi Arabia: an exploratory online cross-sectional survey. [PDF]
Aldosari SA +4 more
europepmc +1 more source
Roadmap for Mental Health Treatment Utilizing Pharmacogenomic Testing: Case Report
Clinical Case Reports, Volume 14, Issue 9, September 2026.
Allison P. Swanson +2 more
wiley +1 more source
ABSTRACT Background Australian‐endorsed general podiatrists and podiatric surgeons (EGPs and EPSs, respectively) operate under a fixed prescribing formulary, the National Podiatry Scheduled Medicines List (NPSML), that restricts access to opioid analgesics including tramadol and tapentadol, despite emerging evidence questioning the efficacy of ...
Lachlan Aquilina +4 more
wiley +1 more source
Pharmacogenomics and Epigenetic Regulation Transforming Pediatric Precision Therapeutics. [PDF]
Satyam SM +9 more
europepmc +1 more source
Digital and Biomarker‐Based Monitoring for Schizophrenia‐Treatment Adherence
Monitoring technologies integrated with artificial intelligence can enable personalized care, improved adherence, and reduced relapses among psychotic patients. ABSTRACT Background Nonadherence to antipsychotics affects nearly half of patients with schizophrenia, leading to rehospitalization, suicidality, and reduced quality of life.
Samuel Inshutiyimana +5 more
wiley +1 more source
Amplicon-based long-read sequencing for accurate CYP2D6 gene deletion and duplication detection using CYP2D7 as a reference gene. [PDF]
Tesfamicael KG +3 more
europepmc +1 more source
The Veterans Aging Cohort Study (VACS)‐National: A Real‐World Data Source Profile
ABSTRACT The Veterans Aging Cohort Study (VACS)‐National is a large, longitudinal real‐world data resource derived from electronic health records within the Department of Veterans Affairs (VA), the largest integrated healthcare system in the United States. As of December 2025, VACS‐National includes > 14.9 million Veterans who have received care in the
Christopher T. Rentsch +13 more
wiley +1 more source

