Results 191 to 200 of about 34,942 (245)

Genetic Landscape of NAT2 in the Moroccan Population: Implications for Isoniazid Pharmacogenetics in Tuberculosis

open access: yesClinical and Translational Science, Volume 19, Issue 8, August 2026.
ABSTRACT The NAT2 gene encodes N‐acetyltransferase 2, an enzyme critically involved in the biotransformation of numerous xenobiotics and aromatic amines, including isoniazid, a cornerstone drug in tuberculosis therapy. Genetic polymorphisms in NAT2 lead to variable acetylation rates, clinically categorized as poor, intermediate, or rapid metabolizer ...
Nada Benyahya   +6 more
wiley   +1 more source

CYP2C19 c.681G>A Is not in Complete Linkage Disequilibrium With c.332‐23A>G: Implications for Pharmacogenetic Testing

open access: yesClinical and Translational Science, Volume 19, Issue 8, August 2026.
ABSTRACT CYP2C19 plays an important role in the metabolism of many medications, including the antiplatelet agent clopidogrel, the antifungal agent voriconazole, selective serotonin reuptake inhibitors, select tricyclic antidepressants, and proton pump inhibitors.
Amy J. Turner   +8 more
wiley   +1 more source

ABCG2 Genetic Variability in Drug Exposure and Toxicity: Implications for Clinical Practice. [PDF]

open access: yesToxics
Božina T   +6 more
europepmc   +1 more source

Operationalizing Next-Generation Sequencing in a Community-Based Academic Cancer Center: Workflow, Integration, and Impact. [PDF]

open access: yesCancers (Basel)
Moorthy G   +19 more
europepmc   +1 more source

Pharmacogenomics: questions and concerns [PDF]

open access: yes, 2005
Mahlknecht, Ulrich   +1 more
core  

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