Results 191 to 200 of about 38,200 (304)

Complexity and Pharmacogenomics [PDF]

The Pharmacogenomics Journal, 2002
J, Licinio, M-L, Wong
openaire   +2 more sources

MT‐RNR1 genotype testing for preventing aminoglycoside‐mediated ototoxicity: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, Volume 92, Issue 9, Page 3002-3011, September 2026.
Aminoglycosides are broad‐spectrum antibiotics used in the management of severe infections. Aminoglycosides are associated with nephrotoxicity and ototoxicity. Although dosing strategies such as once‐daily administration and therapeutic drug monitoring have reduced the incidence of nephrotoxicity, ototoxicity remains unpredictable and may occur at ...
John H. McDermott, Sian Hilton, Cinzia Dello Russo, Nicola Booth, Simon Drysdale, Philip Howard, Stephen Hughes, Mallinath Chakraborty, Helen McDevitt, Charlotte Alston, Maya Desai, Mike Beadsworth, Adam Reynolds, Serim Min, Katherine Payne, Munir Pirmohamed, William G. Newman   +16 more
wiley   +1 more source

Diagnostic BMI and Induction Therapy Weight Change Associated With Hepatotoxicity in Pediatric Patients With Acute Lymphoblastic Leukemia

Cancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Background Hepatotoxicity is a common treatment‐related complication in pediatric acute lymphoblastic leukemia (ALL). Excess adiposity at diagnosis has been identified as a risk factor, but the impact of weight change during therapy has not been examined.
Emily J. Mason, John P. Woodhouse, Jeremy M. Schraw, Joanna S. Yi, Karen R. Rabin, M. Monica Gramatges, Mark C. Zobeck, Baojiang Chen, Melissa B. Harrell, Olga A. Taylor, Michael E. Scheurer, Philip J. Lupo, Van Huynh, Steven D. Mittelman, Etan Orgel, Austin Brown   +15 more
wiley   +1 more source

Introduction. [PDF]

Clin Pharmacol Ther
europepmc   +1 more source

Implementing Pharmacogenomics in Contemporary Hospital Care: Insights from Multidisciplinary Knowledge Exchange. [PDF]

Pharmgenomics Pers Med
Hussainy SY, Conyers R, James PA, Alexander M, Moore C, Fisher S, Gerstman M, Wong AK, Chau S, Clarke A, Philip J, Kirkpatrick CMJ, Lingaratnam S.   +12 more
europepmc   +1 more source

Knowledge and perceptions of pharmacogenomics and personalized medicine among pharmacy students in Gujarat: a cross-sectional survey. [PDF]

J Community Genet
Maheriya B, Thummar K, Chauhan S.
europepmc   +1 more source

GLP‐1 Receptor Agonists and Endoscopy: Understanding Gastric Stasis, Aspiration Risk, and Contemporary Peri‐Procedural Guidance

Chronic Diseases and Translational Medicine, Volume 12, Issue 3, Page 183-196, September 2026.
Pharmacological mechanisms and physiologic effects of GLP‐1 receptor agonists relevant to peri‐endoscopic risk. ABSTRACT The global increase in obesity, type 2 diabetes mellitus (T2DM), and metabolic dysfunction‐associated steatotic liver disease (MASLD) has led to a higher use of glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) among patients ...
Junaid Beig, Jason Ta, Sophie Jones, Emily Scott, Khalid Sofi, Frances Osler, Marije Jansen, Puneet Chhabra   +7 more
wiley   +1 more source

In defence of the drug, two hearts, one profession: Reintegrating medicines expertise and patient-centred care in pharmacy's professional identity. [PDF]

Explor Res Clin Soc Pharm
Davies NM.
europepmc   +1 more source

Multi‐Omics Integration Identifies a Five‐Gene Metabolic Signature With Experimental Validation in Clear Cell Renal Cell Carcinoma

Cancer Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background Clear cell renal cell carcinoma (ccRCC) is hallmarked by profound metabolic reprogramming; however, its intricate crosstalk with the tumor immune microenvironment (TIME) and its clinical ramifications remain inadequately elucidated.
Yi Peng, Suobing Qin, Xiwen Li, Lijun Wan, Rijian Guan   +4 more
wiley   +1 more source

Polygenic risk scores in pharmacogenomics: methodological challenges, current applications, and perspectives for clinical implementation. [PDF]

Med Genet
Mathey CM, Coenen M, Cascorbi I, Hoffmann P.   +3 more
europepmc   +1 more source