Results 181 to 190 of about 34,942 (245)
Medications That Regulate Pregnane X Receptor: A Systematic Review of Current Evidence
Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.PRISMA 2020 flow diagram of study selection for this systematic review of medications that regulate the pregnane X receptor (PXR), from 12 236 records screened to 101 included studies. ABSTRACT The pregnane X receptor (PXR) gene encodes a ligand‐activated protein involved with the metabolism and excretion of drugs, toxins, and other xenobiotics.
Petra Czarniak +4 more
wiley +1 more source
Chronotherapy in Hematological Malignancies: Evaluating the Rationale and Evidence
Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.ABSTRACT Hematological malignancies remain one of the leading causes of morbidity and mortality despite advances in targeted therapies, immunotherapy, and stem cell transplantation. Emerging evidence indicates that treatment efficacy and toxicity depend not only on the choice of therapy but also on its timing relative to the patient's internal ...
Andrej Belančić +7 more
wiley +1 more source
Mixed-Methods Study With a Systematic Review of Personalized Drug Therapy Approaches and Survey Analysis of Pharmacogenomics in Internal Medicine. [PDF]
CureusElachola MS +7 more
europepmc +1 more source
Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 2, August 2026.ABSTRACT Medication burden in older patients with chronic kidney disease (CKD) is substantial, and simple medication counts are insufficient for identifying those at elevated risk of inappropriate prescribing. This study characterized medication burden by assessing the number of medications, potentially inappropriate medications (PIMs) and ...
Morten Baltzer Houlind +4 more
wiley +1 more source
Integration of pharmacogenomics into precision medicine: transforming healthcare for the next generation. [PDF]
Ann Med Surg (Lond)Ali U, Mahato RK.
europepmc +1 more source
British Journal of Pharmacology, Volume 183, Issue 16, Page 4735-4760, August 2026.Abstract Background and Purpose Genomic profiling of patients for genetic variants that modify the effect of specific medications has many benefits, including the possibility of avoiding toxicities and ensuring an adequate effect of the medication. Our intention was to develop a comprehensive, high‐quality pharmacogenetic test panel for clinical use ...
Anna Gréen +5 more
wiley +1 more source
Economic effectiveness of pharmacogenomics-guided prescribing for psychiatric disorders: a systematic review and meta-analysis. [PDF]
Pharmacogenomics JMason ER +5 more
europepmc +1 more source
Clinical and Translational Science, Volume 19, Issue 8, August 2026.ABSTRACT Bridging studies are often waived for orphan diseases such as multiple myeloma (MM) due to challenges in conducting clinical trials in small and heterogeneous populations. However, demographic and regional differences between trial participants and Asian populations may influence drug exposure and response.
Minji Kang +4 more
wiley +1 more source