Results 161 to 170 of about 67,526 (234)

Methotrexate pharmacogenomics [PDF]

Annals of the Rheumatic Diseases, 2006
openaire   +2 more sources

Expanding Access to Genome Sequencing: Higher Diagnostic Yield in Self‐Referred Participants From the CincyKidsSeq Study and Implications for Hybrid Models of Genetic Service Delivery

Clinical Genetics, Volume 109, Issue 4, Page 717-724, April 2026.
Genome sequencing helped find answers for 1 in 5 children with rare conditions in an outpatient study looking at hybrid genetic care delivery. Families who chose testing themselves had the highest diagnostic yield, showing that self‐referral may be a helpful way to improve access to genetic care.
Kristin Theobald, Amelle Shillington, Farrah Jackson, Jaime Lopes, Casey J. Brewer, Brian Dawson, Gang Wu, James Denton, Mike Pauciulo, Xue Zhang, Anne Slavotinek   +10 more
wiley   +1 more source

Pharmacogenomics to optimise psychotropic prescribing: a survey of mental health professionals' perceptions, knowledge, and educational needs. [PDF]

Pharmacogenomics J
Panconesi D, Murtough S, Cotic M, Khani NS, Varney L, Richards-Brown M, Abidoph R, Mills D, Richards-Belle A, Molai J, Fenwick J, Curwen J, Allin M, Berry A, Barczyk M, Bonaccorso S, Griffiths R, Bernini M, Kumar A, Senthilkumar S, Dawda Y, Shokkar R, Murdoch R, Crane J, Rahimi Y, Howard M, Welfare-Wilson A, Secchi A, Thomas C, Pastor B, Sharma P, Pius G, Nazir R, Mir A, Cheshire J, Bostock R, Gibbon S, Singh P, Shah C, Richards S, Cheung SB, Rowe-Leete L, Jibero A, Cox R, Van Driel P, Bramon E.   +45 more
europepmc   +1 more source

Cardiovascular Pharmacogenomics [PDF]

Circulation, 2003
openaire   +2 more sources

Impact of Pharmacokinetic Gene Polymorphisms on Statin‐Induced Myotoxicity in Thai Patients Treated With Simvastatin

Clinical and Translational Science, Volume 19, Issue 4, April 2026.
ABSTRACT Statin‐induced myotoxicity (SIM) is a common adverse effect of simvastatin therapy, which can negatively impact patient adherence and treatment outcomes. This study aims to investigate the impacts of pharmacokinetic (PK) gene polymorphisms on SIM in Thai population treated with simvastatin.
Sayanit Tipnoppanon, Sarawut Siwamogsatham, Yongkasem Vorasettakarnkij, Chonlaphat Sukasem, Pajaree Chariyavilaskul, Patompong Satapornpong, Natchaya Vanwong   +6 more
wiley   +1 more source

The role of pharmacogenomics in the discontinuation of psychotropic medication: a scoping review protocol. [PDF]

HRB Open Res
Stollarova N, Ryan C, Sheaf G, Keating D, O'Donoghue B, Cadogan C.   +5 more
europepmc   +1 more source

Economic effectiveness of pharmacogenomics-guided prescribing for psychiatric disorders: a systematic review and meta-analysis. [PDF]

Pharmacogenomics J
Mason ER, Ali MY, Gibson DS, Murray EK, Burns RM, Kelly C.   +5 more
europepmc   +1 more source

Molecular Testing in Sickle Cell Disease: From Newborn Screening to Transfusion Care

International Journal of Laboratory Hematology, Volume 48, Issue 2, Page 295-304, April 2026.
ABSTRACT Sickle cell disease (SCD) is one of the most frequent monogenic diseases worldwide and a highly heterogeneous and complex disease. SCD care carries several challenges. This includes early and accurate diagnosis as well as optimal red blood cell transfusion matching in this population carrying a high risk of alloimmunization.
Thomas Pincez, Yves D. Pastore
wiley   +1 more source

Integration of pharmacogenomics into precision medicine: transforming healthcare for the next generation. [PDF]

Ann Med Surg (Lond)
Ali U, Mahato RK.
europepmc   +1 more source

ABCB1 Polymorphisms Influence on Temozolomide Resistance and Overall Survival in Glioblastoma Patients: A Systematic Review of Clinical Evidence

Journal of Cellular and Molecular Medicine, Volume 30, Issue 7, April 2026.
ABSTRACT Glioblastoma (GB), defined as IDH‐wildtype CNS WHO grade 4 tumour according to the 2021 WHO classification of CNS tumours, remains a uniformly lethal malignancy in which the efficacy of temozolomide (TMZ) continues to be constrained by both intrinsic tumur biology and the pharmacological barrier imposed by the blood–brain barrier (BBB).
Fabiola De Luca, Deborah Mannino, Anna Paola Capra, Giuliana Ciappina, Marco Donato, Giuseppe Caruso, Emanuela Esposito, Alessio Ardizzone   +7 more
wiley   +1 more source