Results 161 to 170 of about 39,211 (299)

Application and Research Progress of Nucleic Acid‐Based Drug Delivery Systems in the Treatment of Intracerebral Hemorrhage

MedComm – Biomaterials and Applications, Volume 5, Issue 4, December 2026.
This review summarizes recent advances in NADDS for treating ICH, highlighting the advantages and applications of key delivery technologies including lipid nanoparticles, exosomes, and DNA nanostructures. ABSTRACT Intracerebral hemorrhage (ICH) is a devastating stroke subtype associated with high mortality and neurological disability, yet effective ...
Jingyan Wang, Xuejiao Zeng, Pengyu Niu, Jinjin Shi, Wenyan Yu   +4 more
wiley   +1 more source

PHARMWATCH: A Proposed Multilayer Pharmacogenomics Framework for Contextual Star Allele Interpretation. [PDF]

Clin Transl Sci
ABSTRACT The Clinical Pharmacogenetics Implementation Consortium (CPIC) bases its drug‐gene recommendations on the assignment of star alleles, which map known genotypes to defined functional categories and corresponding drug dosage guidelines. The star allele framework, first proposed in 1996 for the CYP gene family and later formalized with CPIC's ...
Eisenhart C, Brickey R, Mewton J.
europepmc   +2 more sources

Shaping the Future of Pharmacology Education: Emerging Directions and International Initiatives From the Seventh International Union of Basic and Clinical Pharmacology Education Satellite Meeting

Pharmacology Research &Perspectives, Volume 14, Issue 6, December 2026.
ABSTRACT The 7th International Union of Basic and Clinical Pharmacology Education Section (IUPHAR‐Ed) Satellite Meeting, held in conjunction with the 20th World Congress of Basic and Clinical Pharmacology in Melbourne, Australia, brought together 99 educators from 18 countries to share innovations and scholarship in pharmacology education.
Clare Guilding, Anna‐Marie Babey, Kellie Charles, Margaret Cunningham, Betty Exintaris, Lynette B. Fernandes, Tina Hinton, Nilushi Karunaratne, Jennifer Koenig, Graham Mackay, Carolina Restini, John L. Szarek, Paul J. White, Kelly Karpa   +13 more
wiley   +1 more source

Pharmacogenomics in the United Arab Emirates: advances in population genomics and challenges in clinical implementation. [PDF]

Front Pharmacol
Haitamar A, Eiyad Abu-Nada S, Wed Eladham M, Mdkhana B, Saheb Sharif-Askari N, Halwani R, Saheb Sharif-Askari F.   +6 more
europepmc   +1 more source

Pharmacogenomics

Annals of Oncology, 2007
openaire   +2 more sources

Aumolertinib Versus Osimertinib as First‐Line Treatment for EGFR‐Mutant Non‐Small Cell Lung Cancer: A Retrospective Real‐World Multicenter Study

International Journal of Cancer, Volume 159, Issue 10, Page 2575-2584, 15 November 2026.
As third‐generation EGFR‐tyrosine kinase inhibitors, both aumolertinib and osimertinib demonstrate clinical efficacy for non‐small cell lung adenocarcinoma, especially in patients with brain metastases. Currently, head‐to‐head studies comparing these two agents in real‐world settings are scarce.
Jinxia Wang, Ping Qi, Jinhua Li, Na Wang, Caihong Fu, Lixin Liu, Shuping Li, Xiao Li, Xiaoming Hou, Hui Qiao   +9 more
wiley   +1 more source

Obstetric pharmacogenomics. [PDF]

J Basic Clin Physiol Pharmacol
Eke AC.
europepmc   +1 more source

ANK1 and EPB41 Variants and The Risk of Glucocorticoid‐Induced Osteonecrosis

Arthritis &Rheumatology, Volume 78, Issue 11, Page 2378-2389, November 2026.
Objective Steroid‐induced osteonecrosis of the femoral head (SONFH) is a refractory skeletal disorder influenced by genetic and environmental factors. However, conclusive pathogenic genetic evidence remains elusive due to the limited exploration of rare damaging variants. In this study, we aimed to identify rare variants associated with SONFH.
Shengbao Chen, Xianmin Zhu, Zhongzhong Chen, Wei Chen, Hussam Alkaissi, Zeng Zhang, Yun Gao, Junhui Yin, Xiangtian Yu, Qiong Fu, Youshui Gao, Zhenzhong Zhu, Qianying Cai, Pengwei Zhang, Weibin Chen, Xin Zhao, Xiaojin Wu, Karel Pacak, Dongxu Jin, Chunde Bao, Zhengping Zhuang, Changqing Zhang   +21 more
wiley   +1 more source

Defining Treatment Response in Pediatric Asthma Pharmacogenomics: Comments on "Gene Polymorphisms Associated with Treatment Response of Asthma in Chinese Children" [Letter]. [PDF]

J Asthma Allergy
Yılmaz E.
europepmc   +1 more source

Monitoring pharmacodynamic and molecular drug targets in liquid biopsy: Exploratory study in liver cancer with modelling of EGFR Receptor engagement

British Journal of Clinical Pharmacology, Volume 92, Issue 11, Page 3902-3913, November 2026.
Abstract Aim Liquid biopsy is minimally invasive (compared with tissue biopsy) and has previously been used to generate systems data regarding drug elimination via hepatic enzymes and transporters. This study extends quantitative assessment of systems parameters in liquid biopsy to pharmacodynamic (PD) and disease markers relevant to cancer development
Zubida M. Al‐Majdoub, Armin Sepp, Amin Rostami‐Hodjegan, Brahim Achour   +3 more
wiley   +1 more source