Results 61 to 70 of about 74,509 (297)

Pharmacogenomics : tailoring drug therapy to individual patients

Journal de la Faculté de Médecine d'Oran
Pharmacogenomics, the study of how individual genetic variations influence drug response, holds tremendous potential for personalized medicine. This comprehensive literature review explores the current landscape of pharmacogenomics, focusing on its role
Eskandar KIROLOS Kirolos
doaj   +1 more source

Pharmacogenomics and gemcitabine

Annals of Oncology, 2006
Approximately half of lung cancer patients present with metastases, and a large proportion will develop recurrent disease, with median survival to cisplatin-based chemotherapy of 11 months. No predictive factor of response to cisplatin-based chemotherapy is yet available in clinical practice.
Carlos Camps, B. Massuti, Dolores Isla, Manuel Cobo, Rafael Rosell   +4 more
openaire   +2 more sources

AI in Neurology: Everything, Everywhere, All at Once Part 3: Surveillance, Synthesis, Simulation, and Systems

Annals of Neurology, EarlyView.
This final part 3 review builds on the practical applications discussed in part 2 and explores how artificial intelligence (AI) is transforming data management, neurological education, and neurological care across large healthcare networks and datasets. The review also highlights AI's role in real‐world and synthetic data, digital twins, and innovative
Matthew Rizzo
wiley   +1 more source

Pharmacogenomics and Opioid Analgesics: Clinical Implications

International Journal of Genomics, 2015
Variation exists in patient response on analgesic treatment in terms of efficacy and safety. This variation may be in part explained by pharmacogenomics.
Eugenia Yiannakopoulou
doaj   +1 more source

Lamivudine and tenofovir pharmacokinetic variability in people with HIV in Papua New Guinea

British Journal of Clinical Pharmacology, EarlyView.
Aims Demographics and kidney function contribute to variability in lamivudine and tenofovir drug concentrations. The aim was to assess, for the first time, the pharmacokinetic variability of lamivudine and tenofovir in Papua New Guinean (PNG) HIV/AIDS patients.
Natália Bordin Andriguetti, Daniel Thomas Barratt, Joseph Tucci, Paul Pumuye, Andrew Alexander Somogyi   +4 more
wiley   +1 more source

Credibility of genetic predictors for antiepileptic drug resistance: A systematic Bayesian reappraisal of published meta‐analyses

British Journal of Clinical Pharmacology, EarlyView.
We systematically reappraised meta‐analyses of pharmacogenetic studies to evaluate the credibility of association between gene polymorphisms and resistance to anti‐epileptic drugs (AEDs). A systematic search was performed in PubMed, Web of Knowledge, Cochrane Library and OpenGrey up to April 2025.
Martina Giacon, Sarah Cargnin, Salvatore Terrazzino   +2 more
wiley   +1 more source

Clinical Knowledge, Attitude, and Perceptions of Community Pharmacists Towards Pharmacogenomics - A Cross-Sectional Study from Saudi Arabia

Pharmacogenomics and Personalized Medicine, 2023
Ziyad Alrabiah, Wajid Syed, Salmeen D Babelghaith, Mohamed N Al Arifi Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi ArabiaCorrespondence: Wajid Syed, Email wali@ksu.edu.saBackground and Aims: It is ...
Alrabiah Z, Syed W, Babelghaith SD, Al Arifi MN   +3 more
doaj  

Pharmacogenomics polygenic risk score for drug response prediction using PRS-PGx methods

Nature Communications, 2022
To try to predict an individual’s drug response using genetic data, most studies have used traditional polygenic risk score (PRS) methods. Here, the authors develop a pharmacogenomics-specific PRS method, which can improve drug response prediction and ...
Song Zhai, Hong Zhang, Devan V. Mehrotra, Judong Shen   +3 more
doaj   +1 more source

Public perceptions of pharmacogenomic services in Ireland - Are people with chronic disease more likely to want service availability than those without? A questionnaire study

Exploratory Research in Clinical and Social Pharmacy, 2022
Background: As pharmacogenomic services begin to emerge in primary care, the insight of the public is crucial for its integration into clinical practice.
Joseph O'Shea, Cristín Ryan, Joseph Gallagher, Claire O'Brien, Conor Morris, Eoin Dwyer, James Mc Laughlin, Laura Fitzpatrick, Maire O'Meara, Sarah Kelly, Sophie Knox, Mark Ledwidge   +11 more
doaj   +1 more source

Pharmacogenetics of analgesic drugs [PDF]

, 2013
• Individual variability in pain perception and differences in the efficacy of analgesic drugs are complex phenomena and are partly genetically predetermined.
Branford, R, Cregg, R, Gubbay, A, Russo, G, Sato, H   +4 more
core   +1 more source