Results 181 to 190 of about 599,269 (342)

High-resolution fecal pharmacokinetic modeling in mice with orally administered antibiotics. [PDF]

Sci Rep
Maskawa R, Takayasu L, Takayasu H, Watanabe K, Takemine S, Kakimoto T, Takeshita K, Narushima S, Suda W, Takayasu M.   +9 more
europepmc   +1 more source

Fospropofol: Pharmacokinetics?

Journal of Anaesthesiology Clinical Pharmacology, 2012
Bharti Mahajan, Sandeep Kaushal, Rajesh Mahajan   +2 more
openaire   +3 more sources

Optogenetic‐Controlled iPSC‐Based Vaccines for Prophylactic and Therapeutic Tumor Suppression in Mice

Advanced Science, EarlyView.
This study develops an a red/far‐red light‐controlled iPSC‐based vaccines (RIVA) based on the chimeric photosensory protein FnBphP and its interaction partner LDB3 for cancer immunotherapy. The RIVA preserves the multiple intrinsic tumor antigens of iPSCs and enables optogenetic control of the expression of the immune adjuvant type I interferon β under
Longliang Qiao, Lingxue Niu, Zhihao Wang, Di Dai, Shasha Tang, Xiaoding Ma, Zhenqiang Deng, Guiling Yu, Yang Zhou, Tao Yan, Xingwan Liu, Deqiang Kong, Linfeng Hu, Xiang Li, Junwei Zhao, Fengfeng Cai, Meiyan Wang, Haifeng Ye   +17 more
wiley   +1 more source

Pharmacokinetic Studies in Animals and Humans of a New Cephalosporin, the Sodium Salt of 7-Cyanacetamidocephalosporanic Acid [PDF]

, 1973
D K Luscombe, Paul J. Nicholls, D. R. Owens, A.D. Russell   +3 more
openalex   +1 more source

PHARMACOKINETICS

British Journal of Anaesthesia, 1981
openaire   +2 more sources

Restoration of SIRT3 Expression in Aged Mice Alleviates UUO‐Induced Renal Fibrosis by Reducing GSK‐3β Hyperacetylation

Advanced Science, EarlyView.
SIRT3 expression is significantly downregulated in the aged kidney, rendering the kidney more vulnerable to fibrotic changes in obstructive nephropathy. By promoting GSK‐3β deacetylation, SIRT3 indirectly inhibits Wnt/β‐catenin signaling, thereby suppressing renal fibrosis.
Jing Wang, Xiang Ren, Huan Lu, Zihao Guo, Xing Li, Yiqun Tian, Yisheng Yin, Zhenliang Qin, Kun Yun, Minglong Wu, Gang Chen, Xiaoyong Zeng   +11 more
wiley   +1 more source

Cefamandole: In Vitro and Clinical Pharmacokinetics

, 1976
R. S. Griffith, Henry R. Black, Gordon Brier, J. D. Wolny   +3 more
openalex   +1 more source

Discovery of Natural Compound α‐Hederin via Large‐Scale Screening as a Targeted JAK/STAT3 Inhibitor for Ovarian Cancer Therapy

Advanced Science, EarlyView.
This study identifies α‐Hederin as a potent dual JAK1/JAK2 inhibitor that blocks STAT3 activation in ovarian cancer. By disrupting STAT3‐driven transcriptional programs, α‐Hederin suppresses tumor proliferation, invasion, and EMT, while enhancing cisplatin efficacy and overcoming chemoresistance.
Jiayu Wang, Pengzhan He, Cheng Liu, Xin Chen, Yilin Tan, Rui Qu, Yan Zhang, Zhou Li, Tailang Yin, Zhinang Yin   +9 more
wiley   +1 more source

Advanced human FcRn knock-in mice for pharmacokinetic profiling of therapeutic antibodies. [PDF]

Sci Rep
Lee S, Kyung M, Park M, Park S, Lee J, Kim S, Lee S, Jo M, Jung ST, Lee HW.   +9 more
europepmc   +1 more source

Effect of hepatic dysfunction and T tube clamping on FK 506 pharmacokinetics and trough concentrations [PDF]

, 1990
Cadoff, E, Fung, JJ, Jain, AB, Krajack, A, Starzl, TE, Todo, S, Venkataramanan, R   +6 more
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