Results 51 to 60 of about 586,923 (192)
Journal of Pharmaceutical Health Care and Sciences, 2019 Background Ritodrine hydrochloride (RD), a β2-adrenergic agonist, is widely used as a tocolytic medication to suppress premature labor, but can cause neonatal hypoglycemia, a potentially severe side effect.
Shoko Shimokawa +7 more
doaj +1 more source
, 2005 Artemisinins were discovered to be highly effective antimalarial drugs shortly after the isolation of the parent artemisinin in 1971 in China. These compounds combine potent, rapid antimalarial activity with a wide therapeutic index and an absence of ...
Haynes, RK, Krishna, S, Woodrow, CJ
core +2 more sources
CPT: Pharmacometrics & Systems Pharmacology, 2021 Quantitative assessment of drug‐drug interactions (DDIs) involving breast cancer resistance protein (BCRP) inhibition is challenged by overlapping substrate/inhibitor specificity.
Chester Costales +9 more
doaj +1 more source
Pharmacokinetics of Cephalexin after Intravenous and Single and Multiple Intramuscular Administration to Rabbit [PDF]
, 2013 Cephalexin is a first generation cephalosporin widely used in rabbits. Its spectrum includes Pasteurella multocida and Staphylococcus aureus. These bacteria, together with Bordetella bronchiseptica, are the main cause of respiratory infections.
Albarellos, Gabriela Alejandra +2 more
core +2 more sources
Optimal designs for random effect models with correlated errors with applications in population pharmacokinetics [PDF]
, 2009 We consider the problem of constructing optimal designs for population pharmacokinetics which use random effect models. It is common practice in the design of experiments in such studies to assume uncorrelated errors for each subject.
Dette, Holger +2 more
core +6 more sources
Pharmaceutics, 2020 Oxaliplatin (L-OHP) is widely prescribed for treating gastroenterological cancer. L-OHP-induced peripheral neuropathy is a critical toxic effect that limits the dosage of L-OHP. An ideal chemotherapeutic strategy that does not result in severe peripheral
Shinji Kobuchi, Risa Shimizu, Yukako Ito
doaj +1 more source
CPT: Pharmacometrics & Systems Pharmacology, 2021 Patients with cardiovascular comorbidity are less tolerant to cardiotoxic drugs and should be treated with reduced doses to prevent cardiotoxicity. However, the safe‐equivalent dose of antitumor drugs in patients with cardiovascular disease/risk is ...
Lan Sang +7 more
doaj +1 more source
Cyclosporine Absorption Following Orthotopic Liver Transplantation [PDF]
, 1986 Blood concentrations of cyclosporine were determined in adult and pediatric patients following orthotopic liver transplantation to quantitate cyclosporine blood clearance and oral absorption.
Beveridge +20 more
core +2 more sources
Pharmacokinetic–pharmacodynamic integration and modelling of oxytetracycline for the calf pathogens Mannheimia haemolytica and Pasteurella multocida [PDF]
, 2018 A calf tissue cage model was used to study the pharmacokinetics (PK) and pharmacodynamics (PD) of oxytetracycline in serum, inflamed (exudate) and noninflamed (transudate) tissue cage fluids.
Aliabadi +45 more
core +1 more source
Pharmacokinetics of recombinant human erythropoietin applied subcutaneously to children with chronic renal failure [PDF]
, 1993 The single-dose pharmacokinetics of recombinant human erythropoietin (rHuEPO) given SC was investigated in 20 patients aged 7-20 years at different stages of chronic renal failure.
Braun, A. +5 more
core +1 more source