Results 81 to 90 of about 5,164,203 (303)

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Pharmacological Activity and Clinical Use of PDRN [PDF]

open access: yesFrontiers in Pharmacology, 2017
PDRN is a proprietary and registered drug that possesses several activities: tissue repairing, anti-ischemic, and anti-inflammatory. These therapeutic properties suggest its use in regenerative medicine and in diabetic foot ulcers. PDRN holds a mixture of deoxyribonucleotides with molecular weights ranging between 50 and 1,500 KDa, it is derived from a
Squadrito, Francesco   +6 more
openaire   +4 more sources

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Antibacterial activity of Methanol and Chloroform extracts of Spilanthes oleracea plant on isolated pathogenic oral bacteria

open access: yesJournal of Applied Sciences and Environmental Management, 2018
Dental caries is an infectious and transmissible disease caused by the colonization of tooth surfaces by normal oral flora, including  Streptococcus and Lactobacillus species.
O. Onoriode, E.O. Oshomoh
doaj   +1 more source

Recent studies on myricetin and its biological and pharmacological activities

open access: yesEXCLI Journal : Experimental and Clinical Sciences, 2023
Priscilla Nadalin   +2 more
doaj   +1 more source

Review on pharmacological activities of liriodenine

open access: yes, 2013
This review describes the pharmacological properties of liriodenine. This alkaloid has been isolated from plant species of many genera and exhibits a wide range of pharmacological activities that have been reported.
Chen, Chung-Yi;Hui-Ming Wu;Wen-Ying Chao;Chien-Hsing Lee
core  

Semisynthesis and pharmacological activities of tetrac analogs: Angiogenesis modulators

open access: yes, 2009
Novel Tetrac analogs were synthesized and then tested. Anti-angiogenesis efficacy was carried out using the Chick Chorioallantoic Membrane (CAM) model and the mouse matrigel model for angiogenesis. Pharmacological activities showed Tetrac can accommodate
Cui, Huadong   +8 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Pharmacological activity of Nilavembu decoction used in Suram (Fever)

open access: yesJournal of Research in Traditional Medicine, 2018
Background: Suram (Fever) is a cardinal response of infection. Nilavembu decoction is used in the treatment of fever in Siddha Medicine and various clinical researches on Nilavembu decoction has reported significant efficacy against viral fever ...
Sujeethasai Krishna, Thayalini Thileepan
doaj   +1 more source

Pharmacological activities of some synthetic peptides related to dermorphin [PDF]

open access: yes, 1997
Objectives: To investigate the relationship between the structure of demorphins (DM) and their pharmacological properties, six analogues of Hyp6DM and Pro6DM were synthesised and their biological activities were studied.
Lakshmana, M.   +3 more
core  

Home - About - Disclaimer - Privacy