Results 241 to 250 of about 9,387,370 (281)
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Journal of Pharmacology & Clinical Toxicology


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Head 438MLB Bhoj R Singh   +3 more
semanticscholar   +1 more source

Clinical pharmacology of etoricoxib

Expert Opinion on Drug Metabolism & Toxicology, 2005
Etoricoxib is a highly selective COX-2 inhibitor (coxib) approved in Europe for the treatment of osteoarthritis (OA), rheumatoid arthritis and acute gouty arthritis. Etoricoxib is an effective analgesic drug that has shown some improved efficacy versus traditional NSAIDs and it is the only coxib approved for the treatment of acute gouty arthritis ...
CAPONE ML   +2 more
openaire   +3 more sources

Epirubicin: a review of the pharmacology, clinical activity, and adverse effects of an adriamycin analogue.

Journal of Clinical Oncology, 1986
Epirubicin (4'-epidoxorubicin) is an antineoplastic agent derived from doxorubicin. The compounds differ in the configuration of the hydroxyl group at the 4' position.
R. J. Cersosimo, W. Hong
semanticscholar   +1 more source

Clinical Pharmacology Of Caffeine

Annual Review of Medicine, 1990
Caffeine is the most widely consumed stimulant drug in the world. This chapter reviews the human pharmacology of caffeine; the evidence for its role in causing human disease, including addiction; and its potential usefulness as a therapeutic agent.
openaire   +3 more sources

Clinical pharmacology and malaria

Annals of Tropical Medicine And Parasitology, 1997
The role of clinical pharmacology in improving the prevention and treatment of malaria is reviewed. A series of general and specific issues is discussed, concentrating on risk-benefit and cost-effectiveness. The techniques of clinical pharmacokinetics play an important role in the optimal use of drugs and this is illustrated by studies on quinine and ...
Alasdair Breckenridge, P. A. Winstanley
openaire   +3 more sources

Sulfasalazine: Pharmacology, Clinical Use, Toxicity, and Related New Drug Development

, 1984
: Sulfasalazine is metabolized by intestinal bacteria, resulting in the release of sulfapyridine and 5-aminosalicylate. The drug is useful in the treatment of active ulcerative colitis as well as in preventing relapses of the disease in remission ...
M. Peppercorn
semanticscholar   +1 more source

CLINICAL PHARMACOLOGY OF BENZODIAZEPINES

Annual Review of Medicine, 1987
The benzodiazepines are the most widely used anxiolytic drugs. Their pharmacokinetic properties differ widely. Side effects are usually mild but dependence can supervene after long-term administration, even if normal therapeutic doses are not exceeded. Careful monitoring of use is essential.
openaire   +2 more sources

The chemistry, pharmacology and clinical pharmacology of diflunisal

Current Medical Research and Opinion, 1978
Studies are reviewed on diflunisal, a new analgesic agent with an improved therapeutic index, compared with acetylsalicylic acid, in animals and humans. Pharmacokinetic data indicate that a twice-daily dosage regimen of diflunisal is adequate for therapeutic purposes.
V. J. Cirillo   +2 more
openaire   +3 more sources

Clinical Pharmacology of Nicotine

Annual Review of Medicine, 1986
Nicotine is the primary reason why people consume tobacco products and it may contribute to causation of tobacco-related diseases. This chapter reviews the human pharmacology of nicotine, the evidence for a role of nicotine in human disease, and the use of nicotine (gum) as a therapeutic agent in smoking cessation therapy.
openaire   +3 more sources

Pharmacology and management of the vitamin K antagonists: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).

Chest, 2008
This article concerning the pharmacokinetics and pharmacodynamics of vitamin K antagonists (VKAs) is part of the American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). It describes the antithrombotic effect of the
J. Ansell   +5 more
semanticscholar   +1 more source

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