Results 51 to 60 of about 9,387,370 (281)
Journal of Analytical Methods in Chemistry, 2022 Mice are the most frequently used animals in pharmacokinetic studies; however, collecting series of blood samples from mice is difficult because of their small sizes and tiny vessels.
Ying Xu +13 more
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Molecular Oncology, EarlyView.TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair +17 more
wiley +1 more source
Zdravniški Vestnik, 2006 Backgrounds: Clinical pharmacology has developed in the second half of 20th century and is now part of an undergraduate and postgraduate studies, being taught as a separate subject on most universities in developed countries.
Jože Drinovec
doaj
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
ANTACIDS CLINICAL PHARMACOLOGY
Journal of V. N. Karazin Kharkiv National University: Series Medicine, 2014 Antacids clinical pharmacology is represented according to the international classification of drugs ATC (anatomical-therapeutic-chemical). The article elucidates antacids indications and contraindications, administration details and side effects.
O. E. Tomina +3 more
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Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
Molecular Oncology, EarlyView.In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
'Seminar-CBL-Ideological and Political Education' Innovative Mode in Clinical Pharmacology Teaching
Xiehe Yixue ZazhiClinical pharmacology is an important discipline that bridges clinical medicine and pharmacology. In the teaching practice, it is necessary to keep up with educational reform and adopt the seminar teaching method combined with case-based learning (CBL ...
DU Ping, LIU He, AN Zhuoling
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Pharmacological Research, 2023 Traditionally, clinical pharmacology has focused its activities on drug-organism interaction, from an individual or collective perspective. Drug efficacy assessment by performing randomized clinical trials and analysis of drug use in clinical practice by
Antonia Agustí +4 more
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Sleep: Physiology, Biochemistry, Psychology, Pharmacology, Clinical Implications
, 1975 In this age of modern era, the use of internet must be maximized. Yeah, internet will help us very much not only for important thing but also for daily activities. Many people now, from any level can use internet.
F. Snyder
semanticscholar +1 more source
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Molecular Oncology, EarlyView.Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source