Results 91 to 100 of about 6,010 (176)

CPT: Pharmacometrics & Systems Pharmacology [PDF]

CPT: Pharmacometrics & Systems Pharmacology, 2013
openaire   +2 more sources

A Pharmacometrics‐Informed Trial Simulation Framework for Optimizing Study Designs for Disease‐Modifying Treatments in Rare Neurological Disorders

CPT: Pharmacometrics & Systems Pharmacology
The development of new treatments for rare neurological diseases (RNDs) may be very challenging due to limited natural history data, lack of relevant biomarkers and clinical endpoints, small and heterogeneous patient populations, and other complexities ...
Yevgen Ryeznik, Ralf‐Dieter Hilgers, Nicole Heussen, Emmanuelle Comets, France Mentré, Niels Hendrickx, Mats O. Karlsson, Andrew C. Hooker, Alzahra Hamdan, Xiaomei Chen, Rebecca Schüle, Matthis Synofzik, Oleksandr Sverdlov   +12 more
doaj   +1 more source

Review of Existing Approaches and Potential Role of Pharmacometrics in the Interpretation of Prognostic Circulating Serum Biomarkers in Advanced NSCLC

Clinical and Translational Science
Circulating serum biomarkers have prognostic value in patients with advanced NSCLC, yet their potential still remains underappreciated at present. This review discusses classical approaches of biomarker data analysis, highlighting gaps, and summarizing ...
Francis Williams Ojara, Yomna M. Nassar, Kimberly Geiger, Madele vanDyk, Stefan Holdenrieder, Markus Joerger, Charlotte Kloft   +6 more
doaj   +1 more source

Population pharmacokinetics and pharmacodynamics of nasal glucagon in patients with type 1 or 2 diabetes

CPT: Pharmacometrics & Systems Pharmacology
The objective was to characterize the pharmacokinetics (PK) and pharmacodynamics (PD) of glucagon after injectable or nasal administration and confirm the appropriate therapeutic dose of nasal glucagon (NG) for adult patients.
Douglas E. James, Tong Shen, Jeanne S. Geiser, Parag Garhyan, Emmanuel Chigutsa   +4 more
doaj   +1 more source

Editorial: Model-informed drug development and evidence-based translational pharmacology

Frontiers in Pharmacology, 2022
Jinxin Zhao, Xiao Zhu, Songwen Tan, Chuanpin Chen, Amal Kaddoumi, Xiu-Li Guo, Yu-Wei Lin, Yu-Wei Lin, Yu-Wei Lin, Yu-Wei Lin, S. Y. Amy Cheung   +10 more
doaj   +1 more source

Causal Directed Acyclic Graphs to Mitigate Confounding Bias in Exposure-Response Analyses. [PDF]

CPT Pharmacometrics Syst Pharmacol
Goulooze SC, Vong C, Hu C, Dumortier T, Mercier F.   +4 more
europepmc   +1 more source

Quantitative Evaluation of Model-Informed Drug Development Implementation in China's Approved Innovative Drugs: From Policy to Practice (2018-2024). [PDF]

CPT Pharmacometrics Syst Pharmacol
Li J, Wang Z, Wei C, He R, Yao Q.
europepmc   +1 more source

Pharmacometrics and/or Systems Pharmacology [PDF]

CPT: Pharmacometrics & Systems Pharmacology, 2019
openaire   +3 more sources

Issue Information

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 4, April 2026.
wiley   +1 more source

Immunogenicity Publication Bias and Its Consequences for Predictive Models: A Call for Transparent Reporting. [PDF]

CPT Pharmacometrics Syst Pharmacol
Tascedda S, Hu Z, Grimm HP, Franssen LC.
europepmc   +1 more source