Results 1 to 10 of about 301,535 (183)
Lack of general learning ability factor in a rat test battery measuring a wide spectrum of cognitive domains [PDF]
Journal of Integrative Neuroscience, 2022 Objective: In the framework of a larger project aiming to test putative cognitive enhancer drugs in a system with improved translational validity, we established a rodent test battery, where different, clinically relevant cognitive domains were ...
Ferenc Kassai +4 more
doaj +1 more source
Cardiovascular Therapeutics, 2022 Background. Multiple studies and meta-analyses examined the role of traditional risk factors for cardiovascular events in statin treatment-naive patients.
Dennis Steenhuis +3 more
doaj +1 more source
Patient Perspectives on the Use of Digital Technology to Help Manage Cystic Fibrosis
Pulmonary Medicine, 2023 Background. Digital health technologies (DHTs) have shown potential to improve health outcomes through improved medication adherence in different disease states.
Alexandre H. Watanabe +6 more
doaj +1 more source
The Investigation of Combined Na+/Ca2+ Exchanger and the L-type Ca2+- Channel Inhibition in Langendorff-Perfused Isolated Guinea Pig Hearts [PDF]
Romanian Journal of Cardiology, 2021 Objective: The sodium/calcium exchanger (NCX) and the L-type Ca2+-channel (LTCC) are nowadays considered the major transmembrane transport mechanisms that control Ca2+ homeostasis.
János PROROK +3 more
doaj +1 more source
Scientific Reports, 2022 The intracerebroventricularly (icv) injected streptozotocin (STZ) induced brain state is a widely used model of sporadic Alzheimer-disease (AD). However, data have been generated in young, naive albino rats.
Attila Gáspár +6 more
doaj +1 more source
Respirology, 2003 The pharmacotherapy for severe acute respiratory syndrome (SARS) is controversial and largely anecdotal. Most patients with suspected SARS should initially be treated with potent antibiotics before proceeding to ‘anti‐SARS’ therapy. There is a spectrum of severity and rate of progression in SARS, and the stages of viral replication, inflammatory ...
Kenneth, Tsang, Nan Shan, Zhong
openaire +2 more sources
Cancer Cell International, 2023 Background KRAS mutations are fraught with the progression of colorectal cancer and resistance to chemotherapy. There are pathways such as extracellular regulated protein kinase 1/2 (ERK1/2) and Akt downstream and farnesylation and geranylgeranylation ...
Masanobu Tsubaki +9 more
doaj +1 more source
Journal of Pharmaceutical Policy and Practice, 2021 Background With the approval of biosimilars for subcutaneously administered products, such as adalimumab, etanercept and insulin, biosimilars become increasingly available in ambulatory care.
Liese Barbier +5 more
doaj +1 more source
Insomnia Pharmacotherapy [PDF]
Neurotherapeutics, 2012 The benzodiazepine receptor agonists (BzRAs) a melatonin receptor agonist and a histamine antagonist have all been approved as hypnotics. Beyond their differing mechanisms of action, they have differences in pharmacokinetics, and among the BzRAs differences in receptor subtype affinity and formulations, which provides the physician with broad options ...
Timothy, Roehrs, Thomas, Roth
openaire +2 more sources
Impact of type of anticoagulant on clinical outcomes in cancer patients who had atrial fibrillation
Scientific Reports, 2023 To date, evidence on optimal anticoagulant options in patients with AF who concurrently have active cancer remains elusive. To describe anticoagulant patterns and clinical outcomes among patients with a concomitant diagnosis of AF and cancer.
Chatree Chai-Adisaksopha +5 more
doaj +1 more source