Results 31 to 40 of about 170,196 (315)

Information needs of physicians regarding the diagnosis of rare diseases: a questionnaire-based study in Belgium

Orphanet Journal of Rare Diseases, 2019
Background Late and misdiagnoses of rare disease patients are common and often result in medical, physical and mental burden for the patient, and financial and emotional burden for the patient’s family.
Liese Vandeborne, Eline van Overbeeke, Marc Dooms, Birgit De Beleyr, Isabelle Huys   +4 more
doaj   +1 more source

Hemokinin-1 is a mediator of chronic restraint stress-induced pain

Scientific Reports, 2023
The Tac4 gene-derived hemokinin-1 (HK-1) binds to the NK1 receptor, similarly to Substance P, and plays a role in acute stress reactions and pain transmission in mice.
Éva Borbély, Angéla Kecskés, József Kun, Eszter Kepe, Barbara Fülöp, Katalin Kovács-Rozmer, Bálint Scheich, Éva Renner, Miklós Palkovits, Zsuzsanna Helyes   +9 more
doaj   +1 more source

The effect of a long-term treatment with cannabidiol-rich hemp extract oil on the adenosinergic system of the zucker diabetic fatty (ZDF) rat atrium

Frontiers in Pharmacology, 2022
Cannabidiol (CBD), the most extensively studied non-intoxicating phytocannabinoid, has been attracting a lot of interest worldwide owing to its numerous beneficial effects.
Gabor Viczjan, Gabor Viczjan, Anna Szilagyi, Barbara Takacs, Ignac Ovari, Reka Szekeres, Vera Tarjanyi, Tamas Erdei, Vanda Teleki, Judit Zsuga, Zoltan Szilvassy, Bela Juhasz, Balazs Varga, Rudolf Gesztelyi   +13 more
doaj   +1 more source

Temporal Trends and Short‐ and Long‐Term Mortality of People With Acute Myocardial Infarction and Rheumatoid Arthritis: A Nationwide Cohort Study

Arthritis Care &Research, EarlyView.
Objective We investigated whether a diagnosis of rheumatoid arthritis (RA) affects the quality of inpatient acute myocardial infarction (AMI) care and long‐term mortality post‐AMI. Methods We analyzed data from 784,091 adults, 6,047 with a diagnosis of RA, from England and Wales hospitalized with AMI between 2005 and 2019 from the Myocardial Ischaemia ...
Megan Butler, Nicholas Weight, Muhammad Rashid, Rodrigo Bagur, Purvi Parwani, Samantha Hider, Edward Roddy, Robert Butler, Mamas A. Mamas   +8 more
wiley   +1 more source

Applicability of drug-related problem (DRP) classification system for classifying severe medication errors

BMC Health Services Research, 2023
Background Several classification systems for medication errors (MEs) have been established over time, but none of them apply optimally for classifying severe MEs.
Carita Linden-Lahti, Anna Takala, Anna-Riia Holmström, Marja Airaksinen   +3 more
doaj   +1 more source

Current issues around the pharmacotherapy of ADHD in children and adults

, 2009
Background New drugs and new formulations enter the growing market for ADHD medication. The growing awareness of possible persistence of ADHD impairment beyond childhood and adolescence resulting in increased pharmacotherapy of ADHD in adults, is also a ...
Tobi, H., Els den Ban, van den Ban, E., Ban, E., van den, Faber, A., Hilde Tobi, Meijer, W.M., Adrianne Faber, Willemijn M. Meijer   +8 more
core   +1 more source

Minimal Important Change and Minimal Clinically Important Difference in Pain and Function With Exercise in Hip Osteoarthritis

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to estimate the minimal important change (MIC) and minimal clinically important difference (MCID) for pain and physical function in individuals with hip osteoarthritis (OA) following a physiotherapist‐guided exercise intervention.
Yareni Guerrero, Fiona Dobson, Venkatesha Venkatesha, Kim Allison, Gabrielle Knox, Libby Spiers, Travis Haber, David J Hunter, Michelle Hall   +8 more
wiley   +1 more source

Tirzepatide, a dual GIP/GLP1-receptor co-agonist preserves cardiac function and improves survival in angiotensin II-induced heart failure model in mice: comparison to liraglutide

Cardiovascular Diabetology
Background Incretin analogues, used for the treatment of type 2 diabetes mellitus and obesity, such as GLP1-receptor agonist liraglutide (Lira) have been shown to reduce major adverse cardiac events in recent clinical trials of heart failure. Tirzepatide
Zsombor I. Hegedűs, Márk E. Jakab, Tamás G. Gergely, Nabil V. Sayour, Andrea Kovács, Sára Antal, Tamás Kovács, Péter Ferdinandy, Zoltán V. Varga, Viktória E. Tóth   +9 more
doaj   +1 more source

Doctor of Philosophy [PDF]

, 2015
dissertationTo compare patient characteristics and healthcare costs between newly-treated DPN patients receiving mono-pharmacotherapy and those receiving combination pharmacotherapy.
Kuo, Kuan-Ling
core  

Update on the pharmacotherapy of obesity.

, 1998
Click on the Resource Link to access the article (may not be free).Objective: To review recent developments in the pharmacotherapy of obesity, including the agents currently approved for use in the management of obesity and those under development. Data
Lomaestro, B M, Malone, M, Cerulli, J
core   +1 more source