Results 31 to 40 of about 131,053 (266)

The effect of a long-term treatment with cannabidiol-rich hemp extract oil on the adenosinergic system of the zucker diabetic fatty (ZDF) rat atrium

Frontiers in Pharmacology, 2022
Cannabidiol (CBD), the most extensively studied non-intoxicating phytocannabinoid, has been attracting a lot of interest worldwide owing to its numerous beneficial effects.
Gabor Viczjan, Gabor Viczjan, Anna Szilagyi, Barbara Takacs, Ignac Ovari, Reka Szekeres, Vera Tarjanyi, Tamas Erdei, Vanda Teleki, Judit Zsuga, Zoltan Szilvassy, Bela Juhasz, Balazs Varga, Rudolf Gesztelyi   +13 more
doaj   +1 more source

Minimal Important Change and Minimal Clinically Important Difference in Pain and Function With Exercise in Hip Osteoarthritis

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to estimate the minimal important change (MIC) and minimal clinically important difference (MCID) for pain and physical function in individuals with hip osteoarthritis (OA) following a physiotherapist‐guided exercise intervention.
Yareni Guerrero, Fiona Dobson, Venkatesha Venkatesha, Kim Allison, Gabrielle Knox, Libby Spiers, Travis Haber, David J Hunter, Michelle Hall   +8 more
wiley   +1 more source

Applicability of drug-related problem (DRP) classification system for classifying severe medication errors

BMC Health Services Research, 2023
Background Several classification systems for medication errors (MEs) have been established over time, but none of them apply optimally for classifying severe MEs.
Carita Linden-Lahti, Anna Takala, Anna-Riia Holmström, Marja Airaksinen   +3 more
doaj   +1 more source

Recent Advances in Ferrite‐Based Materials for Biomedical Applications: A Comprehensive Review

Advanced Materials, EarlyView.
Ferrite nanoplatforms are presented as tunable biomedical materials in which synthesis control, cation engineering, defect/morphology regulation, and surface functionalization govern structure–property–bioactivity relationships. These design strategies enable multifunctional applications including MRI contrast, magnetic hyperthermia, targeted drug ...
Pramod D. Mhase, Varsha C. Pujari, Akash V. Fulari, Sunil M. Patange, Sean Li, Danyang Wang, Sagar E. Shirsath   +6 more
wiley   +1 more source

Tirzepatide, a dual GIP/GLP1-receptor co-agonist preserves cardiac function and improves survival in angiotensin II-induced heart failure model in mice: comparison to liraglutide

Cardiovascular Diabetology
Background Incretin analogues, used for the treatment of type 2 diabetes mellitus and obesity, such as GLP1-receptor agonist liraglutide (Lira) have been shown to reduce major adverse cardiac events in recent clinical trials of heart failure. Tirzepatide
Zsombor I. Hegedűs, Márk E. Jakab, Tamás G. Gergely, Nabil V. Sayour, Andrea Kovács, Sára Antal, Tamás Kovács, Péter Ferdinandy, Zoltán V. Varga, Viktória E. Tóth   +9 more
doaj   +1 more source

Biointegrated Battery‐Based Electroceuticals

Advanced Materials, EarlyView.
Biointegrated batteries go beyond passive power to serve as active therapeutic platforms for delivering programmable electrical cues and bioactive agents. This review examines their mechanisms and applications and provides a framework to guide battery‐based therapeutic design and clinical translation.
Yan Zhou, Zhilian Yue, Zhiqi Chen, Danming Chao, Xiaoteng Jia, Gordon Wallace, Caiyun Wang   +6 more
wiley   +1 more source

Risk Assessment of Drug‐Induced Long QT Syndrome for Some COVID‐19 Repurposed Drugs

Clinical and Translational Science, 2021
The risk‐benefit ratio associated with the use of repurposed drugs to treat severe acute respiratory syndrome‐coronavirus 2 (SARS‐CoV‐2)‐related infectious coronavirus disease 2019 (COVID‐19) is complicated because benefits are awaited, not proven.
Veronique Michaud, Pamela Dow, Sweilem B. Al Rihani, Malavika Deodhar, Meghan Arwood, Brian Cicali, Jacques Turgeon   +6 more
doaj   +1 more source

An Imaging‐Guided, Patient‐Specific Guiding Aid (RWNGuide) for Safe and Reproducible Inner Ear Drug Delivery

Advanced Materials Technologies, EarlyView.
A patient‐specific, imaging‐guided aid enables precise and reproducible drug delivery to the inner ear. By guiding therapeutic agents directly to the round window niche, this approach reduces variability in drug localization, improves delivery safety, and addresses a critical bottleneck in inner ear therapy, offering a scalable strategy for precision ...
Yanjing Luo, Shanshan Jiang, Yimian Luo, Adele Moatti, Farnaz Matin‐Mann   +4 more
wiley   +1 more source

Implementing the flipped classroom model to enhance knowledge retention in pharmacology: a local case study at Semmelweis university

BMC Medical Education
Background The flipped classroom (FC) approach has demonstrated efficacy in enhancing the learning process, including within higher education contexts such as medical education.
Zsófia Onódi, Pál Riba, Péter Ferdinandy, Anikó Görbe, Zoltán V. Varga   +4 more
doaj   +1 more source

Flurbiprofen ameliorated obesity by attenuating leptin resistance induced by endoplasmic reticulum stress

EMBO Molecular Medicine, 2014
Endoplasmic reticulum (ER) stress, caused by the accumulation of unfolded proteins, is involved in the development of obesity. We demonstrated that flurbiprofen, a nonsteroidal anti‐inflammatory drug (NSAID), exhibited chaperone activity, which reduced ...
Toru Hosoi, Rie Yamaguchi, Kikuko Noji, Suguru Matsuo, Sachiko Baba, Keisuke Toyoda, Takahiro Suezawa, Takaaki Kayano, Shinpei Tanaka, Koichiro Ozawa   +9 more
doaj   +1 more source