Results 11 to 20 of about 170,196 (315)

CardiLect: A combined cross‐species lectin histochemistry protocol for the automated analysis of cardiac remodelling

ESC Heart Failure
Background Cardiac remodelling, a crucial aspect of heart failure, is commonly investigated in preclinical models by quantifying cardiomyocyte cross‐sectional area (CSA) and microvascular density (MVD) via histological methods, such as ...
Tamás G. Gergely, Tamás Kovács, Andrea Kovács, Viktória E. Tóth, Nabil V. Sayour, Gábor M. Mórotz, Csenger Kovácsházi, Gábor B. Brenner, Zsófia Onódi, Balázs Enyedi, Domokos Máthé, Przemyslaw Leszek, Zoltán Giricz, Péter Ferdinandy, Zoltán V. Varga   +14 more
doaj   +2 more sources

SARS: pharmacotherapy [PDF]

Respirology, 2003
The pharmacotherapy for severe acute respiratory syndrome (SARS) is controversial and largely anecdotal. Most patients with suspected SARS should initially be treated with potent antibiotics before proceeding to ‘anti‐SARS’ therapy. There is a spectrum of severity and rate of progression in SARS, and the stages of viral replication, inflammatory ...
Kenneth, Tsang, Nan Shan, Zhong
openaire   +2 more sources

Pharmacotherapy for obesity [PDF]

British Journal of Clinical Pharmacology, 2009
Obesity is associated with increased risk of conditions such as hypertension, dyslipidaemia, diabetes mellitus, and obstructive sleep apnoea. Pharmacotherapy for obesity should be considered in combination with lifestyle changes in obese patients, or overweight patients with other conditions that put them at risk of developing heart disease ...
Cheung, BMY, Li, M
openaire   +4 more sources

Estimation of healthcare‐related charges in women with BRCA mutations and breast cancer

BMC Health Services Research, 2021
Background Breast cancer costs were estimated at $16.5 billion in 2010 and were higher than other cancer costs. There are limited studies on breast cancer charges and costs by BRCA mutations and receptor status. We examined overall health care and breast
Joseph Biskupiak, Sudhir Unni, Claire Telford, Minkyoung Yoo, Xiangyang Ye, Rishi Deka, Diana Brixner, David Stenehjem   +7 more
doaj   +1 more source

Dasatinib reverses drug resistance by downregulating MDR1 and Survivin in Burkitt lymphoma cells

BMC Complementary Medicine and Therapies, 2020
Background Current chemotherapies for Burkitt lymphoma (BL) have dramatically improved its clinical outcome. However, chemoresistance can lead to chemotherapy failure and very poor prognosis; thus, novel strategies are urgently required for patients with
Mitsuki Tabata, Masanobu Tsubaki, Tomoya Takeda, Keisuke Tateishi, Katsumasa Tsurushima, Motohiro Imano, Takao Satou, Toshihiko Ishizaka, Shozo Nishida   +8 more
doaj   +1 more source

Regulation of gap junctions by nitric oxide influences the generation of arrhythmias resulting from acute ischemia and reperfusion in vivo.

Frontiers in Pharmacology, 2013
Myocardial ischemia resulting from sudden occlusion of a coronary artery is one of the major causes in the appearance of severe, often life-threatening ventricular arrhythmias.
Ágnes eVégh, Gönczi eMárton, Miskolczi eGottfried, Kovács eMária   +3 more
doaj   +1 more source

In vitro evaluation of antioxidant and neuroprotective effects of curcumin loaded in Pluronic micelles

Biotechnology & Biotechnological Equipment, 2016
Curcumin is a polyphenolic substance with attractive pharmacological activities (e.g. antioxidant, anti-inflammatory, anticancer). Incorporation of curcumin in polymeric micelles could overcome the problems associated with its instability and low aqueous
Cvetelina Gorinova, Denitsa Aluani, Yordan Yordanov, Magdalena Kondeva-Burdina, Virginia Tzankova, Cvetelina Popova, Krassimira Yoncheva   +6 more
doaj   +1 more source

The Nonsteroidal Anti-Inflammatory Drug Ketorolac Alters the Small Intestinal Microbiota and Bile Acids Without Inducing Intestinal Damage or Delaying Peristalsis in the Rat

Frontiers in Pharmacology, 2021
Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) induce significant damage to the small intestine, which is accompanied by changes in intestinal bacteria (dysbiosis) and bile acids.
Barbara Hutka, Bernadette Lázár, András S. Tóth, Bence Ágg, Bence Ágg, Szilvia B. László, Nóra Makra, Balázs Ligeti, Bálint Scheich, Kornél Király, Mahmoud Al-Khrasani, Dóra Szabó, Péter Ferdinandy, Péter Ferdinandy, Klára Gyires, Zoltán S. Zádori   +15 more
doaj   +1 more source

Activation of Serum/Glucocorticoid Regulated Kinase 1/Nuclear Factor-κB Pathway Are Correlated with Low Sensitivity to Bortezomib and Ixazomib in Resistant Multiple Myeloma Cells

Biomedicines, 2021
Multiple myeloma (MM) is an incurable malignancy often associated with primary and acquired resistance to therapeutic agents, such as proteasome inhibitors.
Masanobu Tsubaki, Tomoya Takeda, Takuya Matsuda, Shiori Seki, Yoshika Tomonari, Shoutaro Koizumi, Miki Nagatakiya, Mai Katsuyama, Yuuta Yamamoto, Katsumasa Tsurushima, Toshihiko Ishizaka, Shozo Nishida   +11 more
doaj   +1 more source

Pharmacotherapy of dementia

Vojnosanitetski pregled, 2010
nema
Pavlović Dragan M., Pavlović Aleksandra M., Totić Sanja   +2 more
openaire   +3 more sources