Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
SINTECH (Science and Information Technology) Journal, 2020 Sari Husada Pharmacy is one of the regional companies engaged in drug sales in Demak Regency. The company prioritizes innovation in information technology to face globalization and modern business competition in the industrial era 4.0. Improved services
Arina Nur Syahputri, Dimas Aryo Anggoro
doaj +1 more source
Assessing student perceptions of the Pharm.D. degree at a private tertiary medical university in India [PDF]
, 2017 Background: Pharmacy education in India has expanded to include the Doctorate of Pharmacy degree (Pharm.D.). With clinical practice in early development, job opportunities in India are limited. Graduates often consider pharmacy opportunities abroad. Aims:
Birnie, Christine R. +2 more
core +1 more source
Ethical decision-making, passivity and pharmacy [PDF]
, 2008 Background: Increasing interest in empirical ethics has enhanced understanding of healthcare professionals' ethical problems and attendant decision-making.
Bissell, P., Cooper, R.J., Wingfield, J.
core +1 more source
Imperial strategy of cancer cells through mitochondrial transfer
Molecular Oncology, EarlyView.Cangkrama et al. demonstrated that cancer cells donate their mitochondria to fibroblasts through mitochondrial transfer, reprogramming them into ‘MitoCAF’. Likewise, our group has identified mitochondrial transfer from cancer cells to tumor infiltrating lymphocytes, resulting in mitochondrial ‘hijack’ and impaired antitumor immunity.
Takamasa Ishino, Yosuke Togashi
wiley +1 more source
Delivering and sustaining change through implementation of a lean management system : a journey towards health improvement : a thesis presented in partial fulfilment of the requirements for the degree of Master of Business Studies in Management at Massey University, Albany, New Zealand [PDF]
, 2017 In this ever-changing world organisations seek to be adaptive and innovative and in response they are adopting new ways of working. Approaches to managing change have been well documented and have progressed as a deeper understanding of change and the ...
Winstone, Tim
core
Molecular Oncology, EarlyView.RAS‐targeted therapies have become a clinical reality. Although promising results in patients have been achieved, there are still challenges ahead such as coping with drug resistance. Here we summarize selected RAS inhibitors targeting either individual KRAS mutant isoforms (KRASG12C, KRASG12D, KRASG12V) or exhibiting a wider inhibitory spectrum ...
Matthias Drosten, Mariano Barbacid
wiley +1 more source
2017 Commencement for Jefferson College of Health Professions, Jefferson College of Pharmacy, and Jefferson College of Nursing [PDF]
, 2017 Jefferson College of Health Professions and Jefferson College of Pharmacy Monday, May 22, 10:00 a.m. Processional Trumpet Voluntary, John Stanley The Jefferson Processional, Burle Marx The Reverend R.
core +1 more source
Impact of in-house specialty pharmacy on access to novel androgen axis inhibitors in men with advanced prostate cancer [PDF]
, 2020 Introduction: Novel androgen axis inhibitors are standard of care treatments in advanced prostate cancer. The billed amounts for these medications are often very high, which may create significant financial toxicity for patients and lead to delays in ...
Binder, Adam +4 more
core +1 more source
FEBS Open Bio, EarlyView.Phenotypic plasticity in a newly established set of EGFR inhibitor‐adapted NSCLC cell lines during adaptation and in established cell lines. Here, we introduce novel sublines of the EGFR‐mutant non‐small cell lung cancer (NSCLC) cell lines HCC827 and HCC4006 adapted to the EGFR kinase inhibitors gefitinib (HCC827rGEFI2μm, HCC4006rGEFI1μm), erlotinib ...
Tharsagini V. Nanthaprakash +6 more
wiley +1 more source