Results 91 to 100 of about 76,692 (224)
Aquilaria sinensis MYB‐Like Transcription Factor AsMYB1 Promotes 2‐(2‐Phenylethyl)Chromone Biosynthesis Through Interacting With 14‐3‐3 Family Protein AsGRF1
Plant Biotechnology Journal, EarlyView.ABSTRACT
2‐(2‐Phenylethyl)chromones (PECs) are the primary constituents of agarwood, a valuable aromatic resin widely used in traditional oriental medicine and incense production, exhibiting diverse pharmacological activities. While we have previously reported a polyketide synthase (AsPECPS) playing a crucial role in the biosynthesis of PECs in ...Xinyu Mi, Fanyuan Guan, Yuyan Zheng, Jing Fan, Hailing Qiu, Bowen Gao, Xiao Liu, Juan Wang, Jun Li, Shepo Shi, Xiaohui Wang, Pengfei Tu +11 morewiley +1 more sourceComparison of veterinary drugs and veterinary homeopathy: part 1 [PDF]
, 2017 For many years after its invention around 1796, homeopathy was widely used in people and later in animals. Over the intervening period (1796-2016) pharmacology emerged as a science from Materia Medica (medicinal materials) to become the mainstay of ...AABEL, AHN, ANICK, BEKELMAN, BELL, BELL, BELL, BELLAVITE, BELON, BELON, BOERICKE, CALABRESE, CALABRESE, CALABRESE, CALABRESE, CAMPBELL, CANFIELD, CARTWRIGHT, CHAMBERS, CHAMBERS, CHAN, CHAPMAN, CHIKRAMANE, CONZEMIUS, COWAN, CROSKERRY, CROSKERRY, CUCHERAT, CUNNINGHAM, DAVENAS, DI GIROLAMO, DOEHRING, DOUST, EASTERBROOK, ELIA, ENNIS, ERNST, FLOWER, FRASER, GARTLEHNER, GAY, GODWIN, GOLDACRE, GREGORY, GREGORY, GREGORY, GRIMES, GRUEN, GRUEN, HAHNEMANN, HARTMAN, HEKTOEN, HEKTOEN, HIRST, HOVI, HRÓBJARTSSON, IOANNIDIS, IOANNIDIS, IOANNIDIS, IOANNIDIS, IOANNIDIS, JACOBS, JADAD, JONAS, JONAS, KAHANB, KAHNEMAN, KAYNE, KAYNE, KOHN, LEE, LEES, LEES, LEES, LEXCHIN, LILLEY, LINDE, MADDOX, MATHIE, MATHIE, MATHIE, MATHIE, MATHIE, MATHIE, MATHIE, MATHIE, MATUTE, MCGAURAN, MCKENZIE, MILAZZO, MILGROM, MONTAGNIER, NICOLAI, OWEN, OWEN, OWEN, OWEN, OXTOBY, PAULSON, PINTO, PRASAD, RAO, REILLY, REY, REY, RILEY, ROY, RUDOLF, SACKETT, SAPOSNIK, SARGEANT, SARGEANT, SCHULZ, SHANG, SHAW, SHERR, SHOJANIA, SMITH, SMITH, STERN, TEMGIRE, TOUTAIN, VAN WIJK, VANDENBERG, VIERA, WHITEHEAD, WHITING, WORLD HEALTH, ZOONOSES AND PUBLIC +128 morecore +2 more sourcesThe Jasmonate‐Responsive SmMPK3–SmWRKY33 Module Positively Regulates Tanshinone Biosynthesis in Salvia miltiorrhiza
Plant Biotechnology Journal, EarlyView.ABSTRACT
Tanshinones, the major bioactive diterpenes in Salvia miltiorrhiza Bunge, are widely used to treat cardiovascular and cerebrovascular diseases. While jasmonates (JAs) are known to modulate tanshinones accumulation, the molecular link between JA signalling and tanshinone biosynthesis remains unclear.Renjun Qu, Shiwei Wang, Xinxin Wang, Jiaming Peng, Juan Guo, Guanghong Cui, Tong Chen, Meilan Chen, Shuangshuang Zhao, Ye Shen +9 morewiley +1 more sourceRelieving Sore Throat Formula Exerts a Therapeutic Effect on Pharyngitis through Immunoregulation and NF-κB Pathway
Mediators of Inflammation, 2020 Relieving Sore Throat Formula (RSTF) is a formula approved by the China Food and Drug Administration and has been used for the treatment of pharyngitis in clinic for many years. However, the potential pharmacological mechanism still remains unknown.Yushi Ding, Suyun Yu, Zhonghong Wei, Rui Deng, Peng Chen, Yifan Sun, Qi Jia, Xiaoman Li, Yuanyuan Wu, Wenxing Chen, Kurt S. Zanker, Aiyun Wang, Yin Lu +12 moredoaj +1 more sourceComprehensive Analysis of Bile‐derived Medicinal Materials Based on Ultra‐High‐Performance Liquid Chromatography Coupled With Charged Aerosol Detection and Chemometrics
Analytical Science Advances, Volume 6, Issue 2, December 2025.ABSTRACT
The medicinal use of bile‐derived materials dates back thousands of years. However, due to their complex origins and morphological similarities, adulteration of expensive bile types with cheaper alternatives remains prevalent in the market, significantly compromising quality control and regulatory oversight.Haonan Wu, Xianrui Wang, Fangliang He, Xianlong Cheng, Wenguang Jing, Feng Wei, Tian Yin +6 morewiley +1 more sourceAkebia Saponin D Targeting Ubiquitin Carboxyl‐Terminal Hydrolase 4 Promotes Peroxisome Proliferator‐Activated Receptor Gamma Deubiquitination and Activation of Brown Adipose Tissue Thermogenesis in Obesity
MedComm, Volume 6, Issue 11, November 2025.ASD, a natural plant product screened from small molecule compound library, is an antiobesity agent in mice. ASD promotes BAT thermogenesis to inhibit body weight gain. USP4 was identified and validated as a direct molecular target of ASD. ASD‐induced thermogenesis is modulated by a USP4–PPARγ–UCP1 axis.Lang Chen, Dong‐Hai Liu, Yu‐Xi Li, Song Yang, Wei‐Hua Jia, Liang Peng, Hong‐Lin Liu, Xing‐Bo Wang, Bing Hu, Yu‐Chen Wang, Calvin Pan, Aldons Jake Lusis, Li‐Hong Liu, Li‐Li Gong +13 morewiley +1 more sourceActivation of Spinal Astrocyte α2A Adrenoceptors Protects Against Sepsis‐Induced Heart Injury Through Inhibition of GABAergic Neuronal Necroptosis
Advanced Science, Volume 12, Issue 39, October 20, 2025.The study in this paper found that activating the α2A receptors of astrocytes in the thoracic spinal cord can reduce the release of inflammatory factors, thereby decreasing the necroptosis of GABAergic neurons and consequently alleviating myocardial injury caused by sepsis.Ruilin He, Bin Wu, Liuhu Han, Mingde Li, Wenli Guo, Jiajing Fu, Bin Mei, Eric R. Gross, Xuesheng Liu, Yao Lu +9 morewiley +1 more sourceIdentification of Candidate Biomarkers Correlated With the Pathogenesis and Prognosis of Non-small Cell Lung Cancer via Integrated Bioinformatics Analysis
Frontiers in Genetics, 2018 Background and Objective: Non-small cell lung cancer (NSCLC) accounts for 80–85% of all patients with lung cancer and 5-year relative overall survival (OS) rate is less than 20%, so that identifying novel diagnostic and prognostic biomarkers is urgently ...Mengwei Ni, Xinkui Liu, Jiarui Wu, Dan Zhang, Jinhui Tian, Jinhui Tian, Ting Wang, Shuyu Liu, Ziqi Meng, Kaihuan Wang, Xiaojiao Duan, Wei Zhou, Xiaomeng Zhang +12 moredoaj +1 more sourceTortoise Oligopeptides Augment Cyclophosphamide's Antitumor Activity Through Dual Modulation of Therapeutic Efficacy and Hematologic Toxicity
Food Science &Nutrition, Volume 13, Issue 10, October 2025.Schematic summary of the synergistic antitumor and myeloprotective effects of TOPs in CTX‐treated tumor‐bearing mice, mediated through gut microbiota modulation and direct peptide‐target interactions. CTX, Cyclophosphamide; FMT, Fecal Microbiota Transplantation; S180, S180 tumor cells; TOPs, Tortoise Oligopeptides.Zhuotao Fu, Tian Yu, Cong Meng, Guoni Zhang, Shaojun Huang, Yuping Li, Linchun Fu, Zhitong Deng +7 morewiley +1 more source