Results 11 to 20 of about 84,518 (238)

Inhibition of FAK promotes pancreatic cancer immunotherapy by mediating CXCL10 secretion to enhance CD8<sup>+</sup> T cell infiltration. [PDF]

open access: yesOncoimmunology
Immunotherapy has demonstrated potential in treating various malignant tumors, but its efficacy in pancreatic cancer (PC) remains limited, possibly due to the dense stromal components and immunosuppressive microenvironment of PC.
Shi YC   +6 more
europepmc   +2 more sources

Correction: Aidi injection inhibits the migration and invasion of gefitinib-resistant lung adenocarcinoma cells by regulating the PLAT/FAK/AKT pathway. [PDF]

open access: yesChin Med
Zhang J   +15 more
europepmc   +2 more sources

The complete chloroplast genome of Humulus lupulus cv. ‘Fubei-1’ (Rosales: Cannabaceae)

open access: yesMitochondrial DNA. Part B. Resources, 2021
Hop (Humulus lupulus) is a perennial plant with commercial values. Here, we reported the complete chloroplast genome for a local hop cultivar (Humulus lupulus cv. ‘Fubei-1’) from Xinjiang, China.
Guoping Wang   +6 more
doaj   +1 more source

A novel dammarane triterpenoid alleviates atherosclerosis by activating the LXRα pathway

open access: yesChinese Medicine, 2023
Background We have previously demonstrated that ginsenoside compound K can attenuate the formation of atherosclerotic lesions. Therefore, ginsenoside compound K has potential for atherosclerosis therapy.
Yan Huang   +7 more
doaj   +1 more source

Galangin Exhibits Neuroprotective Effects in 6-OHDA-Induced Models of Parkinson’s Disease via the Nrf2/Keap1 Pathway

open access: yesPharmaceuticals, 2022
Parkinson’s disease (PD) is the second most common neurodegenerative disease, and there is still no cure for it. PD is characterized by the degeneration of dopaminergic neurons, and oxidative stress has been considered an important pathological mechanism.
Qiu-Xu Chen   +8 more
doaj   +1 more source

An advanced network pharmacology study to explore the novel molecular mechanism of Compound Kushen Injection for treating hepatocellular carcinoma by bioinformatics and experimental verification

open access: yesBMC Complementary Medicine and Therapies, 2022
Background Compound Kushen Injection (CKI) is a Chinese patent drug that exerts curative effects in the clinical treatment of hepatocellular carcinoma (HCC).
Shan Lu   +16 more
doaj   +1 more source

A co-crystal berberine-ibuprofen improves obesity by inhibiting the protein kinases TBK1 and IKKɛ

open access: yesCommunications Biology, 2022
The co-crystal berberine-ibuprofen is an effective agent for treating obesity through a reduction of the activity of the non-canonical I κB kinases, IKKε and TBK1.
Man Wang   +8 more
doaj   +1 more source

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