Results 31 to 40 of about 2,719,120 (253)

Bufalin-Loaded PEGylated Liposomes: Antitumor Efficacy, Acute Toxicity, and Tissue Distribution

Nanoscale Research Letters, 2019
Bufalin, derived from Venenum Bufonis, exerts antitumor effects but has low bioavailability and adverse effects when administered as a single agent.
Jiani Yuan, Cheng Zeng, Wei Cao, Xuanxuan Zhou, Yang Pan, Yanhua Xie, Yifang Zhang, Qian Yang, Siwang Wang   +8 more
doaj   +1 more source

A configurable computer simulation model for reducing patient waiting time in oncology departments [PDF]

Health Systems (2022), 2020
Nowadays, the increase in patient demand and the decline in resources are lengthening patient waiting times in many chemotherapy oncology departments. Therefore, enhancing healthcare services is necessary to reduce patient complaints. Reducing the patient waiting times in the oncology departments represents one of the main goals of healthcare manager ...
arxiv   +1 more source

PharmMT: A Neural Machine Translation Approach to Simplify Prescription Directions [PDF]

Findings of EMNLP (2020) 2785--2796, 2022
The language used by physicians and health professionals in prescription directions includes medical jargon and implicit directives and causes much confusion among patients. Human intervention to simplify the language at the pharmacies may introduce additional errors that can lead to potentially severe health outcomes.
arxiv   +1 more source

Tanshinone IIA attenuates the stemness of breast cancer cells via targeting the miR-125b/STARD13 axis

Experimental Hematology & Oncology, 2022
Background Tanshinone II A is an effective component extracted from Salvia miltiorrhiza and the roles of Tanshinone IIA in regulating the stemness of tumor cells remain unclear.
Xiaoman Li, Qi Jia, Yinyin Zhou, Xuan Jiang, Li Song, Yuanyuan Wu, Aiyun Wang, Wenxing Chen, Shijun Wang, Yin Lu   +9 more
doaj   +1 more source

Identification of key pharmacological components and targets for Aidi injection in the treatment of pancreatic cancer by UPLC-MS, network pharmacology, and in vivo experiments

Chinese Medicine, 2023
Background Pancreatic cancer is one of the most lethal cancers worldwide. Aidi injection (ADI) is a representative antitumor medication based on Chinese herbal injection, but its antitumor mechanisms are still poorly understood.
Haojia Wang, Zhishan Wu, Xiaotian Fan, Chao Wu, Shan Lu, Libo Geng, Antony Stalin, Yingli Zhu, Fanqin Zhang, Jiaqi Huang, Pengyun Liu, Huiying Li, Leiming You, Jiarui Wu   +13 more
doaj   +1 more source

GCIP attenuates DOCA/salt-induced cardiac hypertrophy and fibrosis in mice

Di-san junyi daxue xuebao, 2022
Objective To determine the effects of improvement of G alpha q-protein carboxyl terminus imitation polypeptide (GCIP) on deoxycorticosterone acetate (DOCA)/salt-induced cardiac hypertrophy and fibrosis in mice.
TANG Kecheng, LIU Qiao, YANG Shengqian, ZHONG Bin, LUO Qingman, LI Xiaohui   +5 more
doaj   +1 more source

MATERIA MEDICA AND PHARMACY

The American Journal of the Medical Sciences, 1906
Mode of access: Internet.
openaire   +2 more sources

Crosstalks between mTORC1 and mTORC2 variagate cytokine signaling to control NK maturation and effector function

Nature Communications, 2018
The metabolic regulator protein family, mTOR, regulate natural killer (NK) cell development and function, but the underlying mechanism is unclear. Here, the authors show that Raptor/mTORC1 and Rictor/mTORC2 form a feedback crosstalk network to variegate ...
Fangjie Wang, Meng Meng, Banghui Mo, Yao Yang, Yan Ji, Pei Huang, Wenjing Lai, Xiaodong Pan, Tingting You, Hongqin Luo, Xiao Guan, Yafei Deng, Shunzong Yuan, Jianhong Chu, Michael Namaka, Tiffany Hughes, Lilin Ye, Jianhua Yu, Xiaohui Li, Youcai Deng   +19 more
doaj   +1 more source

A Chinese Prescription Yu-Ping-Feng-San Administered in Remission Restores Bronchial Epithelial Barrier to Inhibit House Dust Mite-Induced Asthma Recurrence

Frontiers in Pharmacology, 2020
Clinically, the treatments against asthma like β2 agonist focus on controlling the symptoms rather than inhibiting recurrence radically. This study aims to evaluate the efficacy and mechanism of a potent Chinese prescription Yu-Ping-Feng-San (YPFS ...
Kaifan Bao, Weiyuan Yuan, Yijing Zhou, Yanyan Chen, Xuerui Yu, Xiaoyu Wang, Zhirong Jia, Xi Yu, Xiaotong Wang, Lu Yao, Siqi Wang, Yifan Xu, Yuheng Zhang, Jie Zheng, Min Hong   +14 more
doaj   +1 more source

Capsaicin orchestrates metastasis in gastric cancer via modulating expression of TRPV1 channels and driving gut microbiota disorder

Cell Communication and Signaling, 2023
The association between capsaicin, the major natural pungent compound of chili peppers, and gastric cancer progression has engendered conflicting findings.
Rui Deng, Suyun Yu, Xingqiu Ruan, Huan Liu, Gangfan Zong, Peng Cheng, Ruizhi Tao, Wenxing Chen, Aiyun Wang, Yang Zhao, Zhonghong Wei, Yin Lu   +11 more
doaj   +1 more source