Results 61 to 70 of about 12,160,809 (325)
Using Phase-Field Modeling With Adaptive Mesh Refinement To Study Elasto-Plastic Effects In Phase Transformations [PDF]
, 2008 This thesis details work done in the development of the phase field model which allows simulation of elasticity with diffuse interfaces and the extension of a thin interface analysis developed by previous authors to study non-dilute ideal alloys ...
Greenwood, Michael
core
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
EnergiesReliable performance of TRISO (tristructural isotropic) nuclear fuel depends on the interplay between its multilayer architecture and the buffer-layer microstructure, which are difficult to isolate experimentally.
Merve Gencturk, Karim Ahmed
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Il metodo Phase-Field per la simulazione della propagazione delle cricche [PDF]
, 2022 Il metodo Phase-Field è uno dei più promettenti e innovativi nell'ambito della meccanica della frattura. In questo elaborato viene descritto dal punto di vista teorico e si implementa in MATLAB una versione che tiene conto in modo "automatico" dell ...
Reviezzo, Alessandro
core
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
MathematicsThe main objective of this work was to model the failure mechanisms of brittle materials subjected to thermal and mechanical loads. A diffusive representation of the crack topology provides the basis for the regularized kinematic framework used.
Lotfi Ben Said +5 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
CrystalsDiscontinuous dynamic recrystallization is a critical microstructural evolution mechanism during high-temperature deformation, influencing material properties significantly.
Alireza Rezvani +2 more
doaj +1 more source