Results 111 to 120 of about 22,441,409 (292)

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Phase field modelling of elastic-plastic fatigue fracture of oil and gas pipeline

Materials Research Express
This paper established a fatigue fracture phase-field model (PFM) to evaluate fatigue damage evolution and crack propagation in oil and gas pipeline.
Zhen Wang, Wei He, Xin Li, Tao Lu, Shengguo Chen, Dingyu Li, Hengwei Zheng   +6 more
doaj   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

Molecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani, Laura Mariën, Caro De Weerdt, Sanne Wouters, Laure‐Anne Teuwen, Hans Prenen, Katleen Janssens, Timon Vandamme   +7 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Convection effect on dendritic growth using phase-field method [PDF]

China Foundry, 2010
Phase-field model was employed to quantitatively study the effect of convection on pattern selection and growth rate of 2D and 3D dendrite tip, as well as the effect of the different convection velocity on the dendritic growth.
Zhu Changsheng, Wang Zhiping, Gui Jin
doaj  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Numerical prediction of mechanical properties of dual-phase steel by using multi-phase-field method and homogenization method [PDF]

, 2011
In this study, a numerical prediction method by combining the crystal plasticity finite element method, the multi-phase-field method and the homogenization method is developed to predict microstructure formation and mechanical property of the dual-phase (
Yamanaka, A., Takaki, T.
core  

Phase field methods of fracture in heterogeneous media and structures: a combined bulk-interface-like crack method

, 2019
Heterogeneity is present in most of natural and engineering systems. In this contribution, I present the recent developments of a combined phase field method for bulk fracture and interface-like cracks.
Reinoso, Jose
core   +1 more source

An Electrohydrodynamic Phase-Field Model for Contact Angle Hysteresis in Electrowetting Pixels: Decoupling Physical Pinning and Charge Trapping

Micromachines
Precise manipulation of two-phase flow in micro-confined electrowetting pixels is limited by contact angle hysteresis (CAH). To elucidate this non-equilibrium process, we establish a high-fidelity electrohydrodynamic (EHD) phase-field simulation ...
Qingsong Lu, Li Wang, Feng Li, Yanjun Yang, Qifu Liu, Xinying Wang, Feng Chi, Liming Liu, Zichuan Yi   +8 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source