Results 71 to 80 of about 941,423 (318)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

An Efficient Control of a Series Connected Two-Synchronous Motor 5-Phase with Non Sinusoidal EMF Supplied by a Single 5-leg VSI: Experimental and Theoretical Investigations [PDF]

, 2012
Lien vers la version finale éditeur This paper proposes the control scheme of an original drive which is made up of two 5-phase permanent magnet synchronous machines (PMSM) connected in series.
CHARPENTIER, Jean-Frederic, MEKRI, Fatiha, SEMAIL, Eric, Charpentier, Jean Fréderic   +3 more
core   +1 more source

Control of Acoustic Cavitation for Efficient Sonoporation with Phase-Shift Nanoemulsions

Ultrasound in Medicine & Biology, 2019
Acoustic cavitation can be used to temporarily disrupt cell membranes for intracellular delivery of large biomolecules. Termed sonoporation, the ability of this technique for efficient intracellular delivery (i.e., >50% of initial cell population showing uptake) while maintaining cell viability (i.e., >50% of initial cell population viable) has proven ...
Mark T, Burgess, Tyrone M, Porter
openaire   +3 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Research of single phase-shift close-loop control for bi-directional full-bridge DC-DC converter

Gong-kuang zidonghua, 2014
In view of problem of low efficiency of bi-directional full-bridge DC-DC converter based on traditional single phase-shift control, the paper proposed a design scheme of bi-directional full-bridge DC-DC converter based on single phase-shift close-loop ...
YANG Xiaokang, LI Hequn, GAO Qiaomei, CHENG Hong   +3 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Impact of PWM strategies on RMS current of the DC-link Voltage Capacitor of a dual-three phase drive [PDF]

, 2014
The major drawback of usual dual three-phase AC machines, when supplied by a Voltage Source Inverter (VSI), is the occurrence of extra harmonic currents which circulate in the stator windings causing additional losses and constraints on the power ...
ROUHANA, Najib, DUGUEY, Jean-François, Jean-Francois Duguey, SEMAIL, Eric, Eric Semail, Najib Rouhana   +5 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

DAB minimum current stress segmented optimal control strategy based on extended phase shift control

电力工程技术
To address the issue of low transmission efficiency in dual active bridge (DAB) converters during electric vehicle charging and discharging processes, a minimum current stress optimization control strategy combining the differential extremum method with ...
Xingguo TAN, Chaomeng LI, Gaoming FENG, Xin ZHAO, Liangliang SUN   +4 more
doaj   +1 more source