Results 81 to 90 of about 2,092,870 (303)

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

An Efficiency-Optimized Isolated Bidirectional DC-DC Converter with Extended Power Range for Energy Storage Systems in Microgrids

Energies, 2012
This paper proposes a novel extended-single-phase shift (ESPS) control strategy of isolated bidirectional full-bridge DC-DC converters (IBDCs) which are a promising alternative as a power electronic interface in microgrids with an additional function of ...
Xiaolong Shi, Jiuchun Jiang, Xintao Guo
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

DAB minimum current stress segmented optimal control strategy based on extended phase shift control

电力工程技术
To address the issue of low transmission efficiency in dual active bridge (DAB) converters during electric vehicle charging and discharging processes, a minimum current stress optimization control strategy combining the differential extremum method with ...
Xingguo TAN, Chaomeng LI, Gaoming FENG, Xin ZHAO, Liangliang SUN   +4 more
doaj   +1 more source

Phase-Shift Control for Enhancing Misalignment Tolerance in UCA-Based OAM-MIMO Systems

IEEE Access
This paper presents a novel approach for achieving high-capacity transmission utilizing sub-terahertz (THz) radio orbital angular momentum (OAM) multiplexing, specifically in scenarios where the radio link is susceptible to antenna misalignment. We focus
Norifumi Kamiya, Masahiro Kawai, Eisaku Sasaki   +2 more
doaj   +1 more source

Progress in Atomic Fountains at LNE-SYRTE [PDF]

, 2012
We give an overview of the work done with the Laboratoire National de M\'etrologie et d'Essais-Syst\`emes de R\'ef\'erence Temps-Espace (LNE-SYRTE) fountain ensemble during the last five years.
A. Clairon, A. Clairon, A. Clairon, A. Clairon, A. Clairon, A. Clairon, A. Clairon, A. Clairon, A. Clairon, A. Clairon, A. Clairon, A. Clairon, A. Clairon, B. Chupin, B. Chupin, B. Chupin, B. Chupin, B. Chupin, B. Chupin, B. Chupin, B. Chupin, B. Chupin, B. Chupin, B. Chupin, B. Chupin, B. Chupin, D Rovera, D Rovera, D Rovera, D Rovera, D Rovera, D Rovera, D Rovera, D Rovera, D Rovera, D Rovera, D Rovera, D Rovera, D. Rovera, G. Santarelli, G. Santarelli, G. Santarelli, G. Santarelli, G. Santarelli, G. Santarelli, G. Santarelli, G. Santarelli, G. Santarelli, G. Santarelli, G. Santarelli, G. Santarelli, G. Santarelli, J. Guena, J. Guéna, J. Guéna, J. Guéna, J. Guéna, J. Guéna, J. Guéna, J. Guéna, J. Guéna, J. Guéna, J. Guéna, J. Guéna, J. Guéna, K. Gibble, K. Gibble, K. Gibble, K. Gibble, K. Gibble, K. Gibble, K. Gibble, K. Gibble, K. Gibble, K. Gibble, K. Gibble, K. Gibble, K. Gibble, M. Abgrall, M. Abgrall, M. Abgrall, M. Abgrall, M. Abgrall, M. Abgrall, M. Abgrall, M. Abgrall, M. Abgrall, M. Abgrall, M. Abgrall, M. Abgrall, M. Abgrall, M. E. Tobar, M. Lours, M. Lours, M. Lours, M. Lours, M. Lours, M. Lours, M. Lours, M. Lours, M. Lours, M. Lours, M. Lours, M. Lours, M. Lours, M.E. Tobar, M.E. Tobar, M.E. Tobar, M.E. Tobar, M.E. Tobar, M.E. Tobar, M.E. Tobar, M.E. Tobar, M.E. Tobar, M.E. Tobar, M.E. Tobar, M.E. Tobar, P. Laurent, P. Laurent, P. Laurent, P. Laurent, P. Laurent, P. Laurent, P. Laurent, P. Laurent, P. Laurent, P. Laurent, P. Laurent, P. Laurent, P. Laurent, P. Rosenbusch, P. Rosenbusch, P. Rosenbusch, P. Rosenbusch, P. Rosenbusch, P. Rosenbusch, P. Rosenbusch, P. Rosenbusch, P. Rosenbusch, P. Rosenbusch, P. Rosenbusch, P. Rosenbusch, P. Rosenbusch, R. Li, R. Li, R. Li, R. Li, R. Li, R. Li, R. Li, R. Li, R. Li, R. Li, R. Li, R. Li, Ruoxin Li, , S. Bize, S. Bize, S. Bize, S. Bize, S. Bize, S. Bize, S. Bize, S. Bize, S. Bize, S. Bize, S. Bize, S. Bize, S. Bize   +168 more
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

An Improved AC-Link Voltage Matching Control for the Multiport Modular Multilevel DC Transformer in MVDC Applications

Energies
In this paper, an improved AC-link voltage matching control (IVM) strategy is proposed for the multiport modular multilevel DC transformer (M3DCT), which comprises a single-phase modular multilevel converter (MMC) and a series of cascaded H-bridge units.
Yong Chen, Songtao Yu, Yizhen Wang, Ruixiong Yang, Xu Cheng   +4 more
doaj   +1 more source

Deterministic and cascadable conditional phase gate for photonic qubits

, 2012
Previous analyses of conditional \phi-phase gates for photonic qubits that treat cross-phase modulation (XPM) in a causal, multimode, quantum field setting suggest that a large (~\pi rad) nonlinear phase shift is always accompanied by fidelity-degrading ...
Chuang, Isaac L., Chudzicki, Christopher, Shapiro, Jeffrey H.   +2 more
core   +1 more source