Results 71 to 80 of about 15,413,531 (300)

Approximation of Cumulative Distribution Functions by Bernstein Phase-Type Distributions

Performance Evaluation
The inclusion of generally distributed random variables in stochastic models is often tackled by choosing a parametric family of distributions and applying fitting algorithms to find appropriate parameters. A recent paper proposed the approximation of probability density functions (PDFs) by Bernstein exponentials, which are obtained from Bernstein ...
András Horváth, Illés Horváth, Marco Paolieri, Miklós Telek, Enrico Vicario   +4 more
openaire   +4 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Comrade Black Distribution [February 1998 catalogue]

, 1998
The catalog of a D.I.Y. retail distributor of political and small press books and pamphlets. Started in 1996, CB Distribution is an effort to counter the homogeneity of political and artistic thought that dominates the mainstream media.
Comrade Black Distribution
core   +1 more source

A Reliability Modeling Method Based on Phase-Type Distribution Aiming at Shock Model

IEEE Access, 2020
The traditional shock model generally describes the magnitude of the cumulative damage caused by a random shock sequence and compares the magnitude with a predetermined threshold to obtain the failure time of a component.
Long Wang, Xu Luo, Yue Li, Jia Tang
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Clustering patient length of stay using mixtures of Gaussian models and phase type distributions

, 2009
Gaussian mixture distributions and Coxian phase type distributions have been popular choices model based clustering of patients' length of stay data.
Millard, P.H., McClean, S.I., El-Darzi, E., Garg, L., Meenan, B.   +4 more
core   +1 more source

Investigation of the Fork–Join System with Markovian Arrival Process Arrivals and Phase-Type Service Time Distribution Using Machine Learning Methods

Mathematics
This paper presents a study of fork–join systems. The fork–join system breaks down each customer into numerous tasks and processes them on separate servers. Once all tasks are finished, the customer is considered completed.
Vladimir Mironovich Vishnevsky, Valentina Ivanovna Klimenok, Aleksandr Mikhailovich Sokolov, Andrey Alekseevich Larionov   +3 more
doaj   +1 more source

Classification and properties of acyclic discrete phase-type distributions based on geometric and shifted geometric distributions

Journal of Industrial Engineering International, 2018
Acyclic phase-type distributions form a versatile model, serving as approximations to many probability distributions in various circumstances. They exhibit special properties and characteristics that usually make their applications attractive.
Mohsen Varmazyar, Raha Akhavan-Tabatabaei, Nasser Salmasi, Mohammad Modarres   +3 more
doaj   +1 more source

Sequence Discrimination Using Phase-Type Distributions [PDF]

, 2006
We propose in this paper a novel approach to the classification of discrete sequences. This approach builds a model fitting some dynamical features deduced from the learning sample. These features are discrete phase-type (PH) distributions. They model the first passage times (FPT) between occurrences of pairs of substrings.
Jérôme Callut, Pierre Dupont
openaire   +2 more sources

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source