Results 91 to 100 of about 15,413,531 (300)
The least variable phase type distribution is erlang
Let \((X_ t,t\geq 0)\) be a continuous-time Markov process with state space \(\{\) 0,1,...,n\(\}\) where 0 is an absorbing state, and let \(T_{n0}\) denote the time to reach 0 if \(X_ 0=n\). It is shown that \(var(T_{n0})/(E T_{n0})\) \(2\geq 1/n\) with equality if and only if \((X_ t,t\geq 0)\) is a pure death process with constant death rate.
David, Aldous, Larry, Shepp
openaire +3 more sources
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Finite time ruin probabilities with one Laplace inversion. [PDF]
In this work we present an explicit formula for the Laplace transform in time of the finite time ruin probabilities of a classical Levy model with phase-type claims. Our result generalizes the ultimate ruin probability formula of Asmussen and Rolski [IME
Avram, Florin, Usábel, Miguel A.
core
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
An investigation of emerin and nuclear lamins: : Interactions, distribution, and role in cell cycle regulation, in cells derived from EDMD patients. [PDF]
Emery Dreifuss muscular dystrophy (EDMD) is caused by mutations either in the gene encoding emerin or in the gene encoding A-type lamins (lamins A and C).
Maria, Choleza
core
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Information matrix test An application using Pareto’s original income distribution data
This article attempts to apply and interpret the correspondent Identification Matrix test (White, 1982) for a Pareto type I distribution. One of the most cited datasets used by Pareto, England’s income distribution in 1843 and in 1879, is used.
Mattos, Enlinson, Ponczek, Vladimir
core
Three-phase fast decoupled power flow for distribution networks
Power system single-phase models assume that generation, transmission and distribution systems are perfectly balanced. The great appeal of this type of model is its simplicity, for all the calculations become quite simple, when compared with the three ...
Zago, MG, Garcia, AV
core +1 more source
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Many-server queues with customer abandonment: Numerical analysis of their diffusion model
We use a multidimensional diffusion process to approximate the dynamics of aqueue served by many parallel servers. Waiting customers in this queue may abandonthe system without service.
Shuangchi He, Jim Dai
doaj

