Results 81 to 90 of about 5,043,419 (253)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

REVISIÓN DE APLICACIONES DE TERMODINÁMICA CONTINUA EN EL EQUILIBRIO DE FASES DE MEZCLAS COMPLEJAS

Avances en Ciencias e Ingeniería, 2020
This documentary review studies scientific research on continuous thermodynamics applications in phase equilibrium calculations of complex mixtures with the purpose of comparing and establishing relations between the types of complex mixture ...
María Lucena, Yris González, Wilfredo Angulo, Iván Machin   +3 more
doaj  

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

The Role of Three-Body Interactions on the Equilibrium and Non-Equilibrium Properties of Fluids from Molecular Simulation [PDF]

The aim of this work is to use molecular simulation to investigate the role of three-body interatomic potentials in noble gas systems for two distinct phenomena: phase equilibria and shear flow.
Marcelli, Gianluca
core  

Phase equilibrium law of CO₂ storage in depleted gas reservoirs

Youqicang pingjia yu kaifa, 2023
In the process of CO2 injection and storage of a single well in depleted gas reservoirs, the injected CO2 causes the rebalance among gas, water and solid, and the accompanying CO2 dissolution, water evaporation and salting out affect the physical ...
YANG Yu, XU Qilin, LIU Ronghe, HUANG Dongjie, YAN Ping, WANG Jianmeng   +5 more
doaj  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Calculation of Maximum Water Content in Various Natural Gases by Using Modified Peng-Robinson Equation of State

Communications, 2012
During the expansion of natural gas in the pipeline, the gas cools down due to the Joule-Thomson effect and due to the interaction between pipeline system and its surroundings to the conditions at which gas is saturated by water vapors, and gas is not ...
Jan Rajzinger
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Phase equilibrium and insulin partitioning in aqueous two-phase systems containing block copolymers and potassium phosphate

, 2015
In this work, phase diagrams of aqueous two-phase systems (ATPS) containing PEO-PPO-PEO block copolymers and potassium phosphate as well as the partitioning behavior of insulin in these systems are presented.
Pessoa, PA, Mohamed, RS, Loh, W, Haraguchi, LH   +3 more
core   +1 more source

Требования к метану как к топливу для жидкостных ракетных двигателей

Химическая безопасность
В статье рассмотрены требования к метану как топливу для жидкостных ракетных двигателей, сформированные по результатам анализа нормативной базы, оценки влияния примесей на криогенные и теплофизические характеристики топлива, а также исследования свойств ...
Шаповалова, О.В., Петрова, А.А., Степанов, А.В., Ахременков, Б.В., Головань, С.Е.   +4 more
doaj   +1 more source