Results 61 to 70 of about 11,578,760 (276)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Dislocation dynamics and crystal plasticity in the phase-field crystal model

Physical Review B, 2018
11 pages, 3 ...
Skaugen, Audun, Angheluta, Luiza, Vinals, Jorge   +2 more
openaire   +4 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Chiral magnonic edge states in ferromagnetic skyrmion crystals controlled by magnetic fields

Physical Review Research, 2020
Achieving control over magnon spin currents in insulating magnets, where dissipation due to Joule heating is highly suppressed, is an active area of research that could lead to energy-efficient spintronics applications.
Sebastián A. Díaz, Tomoki Hirosawa, Jelena Klinovaja, Daniel Loss   +3 more
doaj   +1 more source

Liquid crystal cells based on photovoltaic substrates [PDF]

Journal of the European Optical Society-Rapid Publications, 2016
Liquid crystal cells with LiNbO3:Fe crystals as substrates, are described. The photovoltaic field generated by the substrates is able to reorient the liquid crystal director thus giving rise to a phase shift on the light propagating through the cell, as ...
Lucchetti L., Kushnir K., Zaltron A., Simoni F.   +3 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Photonic crystal waveguides in chalcogenide glasses [PDF]

, 2011
The growing speed and bandwidth requirements of telecommunication systems demand all-optical on-chip solutions. Microphotonic devices can deliver low power nonlinear signal processing solutions. This thesis looks at the slow light photonic crystals in
Spurny, Marcel
core   +2 more sources

Unraveling the Determinant Mechanisms in Flow-Mediated Crystal Growth and Phase Behaviors

Crystals
To uncover the critical mechanisms responsible for mesoscopic level development during flow-mediated crystal growth, we develop a semi-two-way hydrodynamic coupled structural phase-field crystal formalism (HXPFC-s2).
L. Connor Willis, Tesia D. Janicki, Rekha R. Rao, Z. Leonardo Liu   +3 more
doaj   +1 more source

A New L²-Gradient Flow-Based Fractional-in-Space Modified Phase-Field Crystal Equation and Its Mass Conservative and Energy Stable Method

Fractal and Fractional, 2022
In this paper, we introduce a new fractional-in-space modified phase-field crystal equation based on the L2-gradient flow approach, where the mass of atoms is conserved by using a nonlocal Lagrange multiplier.
Hyun Geun Lee
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source