Results 91 to 100 of about 1,799,934 (343)

MRI using radiofrequency magnetic field phase gradients

Magnetic Resonance in Medicine, 2009
AbstractConventionally, MR images are formed by applying gradients to the main static magnetic field (B0). However, the B0 gradient equipment is expensive, power‐hungry, complex, and noisy and can induce eddy currents in nearby conducting structures, including the patient.
Sharp, Jonathan C., King, Scott B.
openaire   +4 more sources

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

A practical density functional for polydisperse polymers

, 2001
The Flory Huggins equation of state for monodisperse polymers can be turned into a density functional by adding a square gradient term, with a coefficient fixed by appeal to RPA (random phase approximation). We present instead a model nonlocal functional
, , De Gennes P.-G, Doi M., I Pagonabarraga, Joanny J. F., M. E Cates, Pagonabarraga I., Sollich P.   +8 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Phase Extraction Algorithm Based on the Spatial Carrier-Frequency Phase-Shifting Gradient

IEEE Photonics Journal, 2019
For improving the accuracy and processing speed of phase extraction, a new phase extraction algorithm based on the spatial carrier-frequency phase-shifting gradient (SCFPS-G) is proposed.
Haoren Zou, Liyun Zhong, Jiaosheng Li, Zhenda Sun, Yicheng Liu, Qinwen Ning, Xiaoxu Lu   +6 more
doaj   +1 more source

Nonlinear Analysis of the Eckhaus Instability: Modulated Amplitude Waves and Phase Chaos with Non-zero Average Phase Gradient

, 2001
We analyze the Eckhaus instability of plane waves in the one-dimensional complex Ginzburg-Landau equation (CGLE) and describe the nonlinear effects arising in the Eckhaus unstable regime.
Alessandro Torcini, Aranson, Aranson, Bar, Bot, Bot, Brusch, Brusch, Büttiker, Chang, Chaté, Conte, Cross, Daviaud, Egolf, Garnier, Janiaud, Kness, Liu, Liu, Lutz Brusch, Markus Bär, Montagne, Montagne, Mukolobwiez, Mutabazi, Or-Guil, Ouyang, Ouyang, Porubov, Sakaguchi, Shraiman, Stuart, Torcini, Torcini, van Hecke, van Hecke, Vince, Weber, Wierschem, Zhou   +40 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Direct measurement of quantum phase gradients in superfluid 4He flow

, 2007
We report a new kind of experiment in which we generate a known superfluid velocity in a straight tube and directly determine the phase difference across the tube's ends using a superfluid matter wave interferometer. By so doing, we quantitatively verify
Aditya Joshi, C. F. Barenghi, D. R. Tilley, F. London, J. Clarke, J. S. Langer, L. D. Landau, R. J. Donnelly, R. J. Donnelly, R. P. Feynman, Richard Packard, Yuki Sato   +11 more
core   +1 more source