Results 91 to 100 of about 1,280,007 (347)

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Precision Construction of Chiral Optical Fields with Nine Controllable Degrees of Freedom

Advanced Photonics Research
Recently, chiral optical fields (COFs) have garnered significant attention due to their multiple controllable degrees of freedom (DOFs), enabling applications in diverse areas such as optical tweezers, manufacturing, and holographic encryption.
Duo Deng, Xing Liu, Zixin Xu, Zhenjun Yang, Yan Li   +4 more
doaj   +1 more source

Design and Analysis of Three-Phase Three-Level PWM Inverter [PDF]

, 2010
Design of three-phase three level PWM inverter and analysis of the output current harmonics are presented in this paper. The three-level inverter is designed to supply three-phase load and it is controlled by FPGA under several modulation techniques ...
Dahono, Pekik Argo
core  

Multi-user Communication in Difficult Interference

, 2019
The co-channel interference (CCI) is one of the major impairments in wireless communication. CCI typically reduces the reliability of wireless communication links, but the difficult CCI which is no more or less strong to the desired signals destroys ...
Basnayaka, Dushyantha A., Ratnarajah, Tharmalingam   +1 more
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

An extensive photometric study of the Blazhko RR Lyrae star RZ Lyr

, 2012
The analysis of recent, extended multicolour CCD and archive photoelectric, photographic and visual observations has revealed several important properties of RZ Lyr, an RRab-type variable exhibiting large-amplitude Blazhko modulation. On the time-base of
Belucz, B., Dózsa, Á., Fehér, V., Görög, N., Hajdu, G., Jurcsik, J., Kriskovics, L., Kun, E., Kővári, Zs., Molnár, L., Nagy, I., Posztobányi, K., Smitola, P., Szeidl, B., Sódor, Á., Vida, K.   +15 more
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Laser-induced speckle scatter patterns in Bacillus colonies

Frontiers in Microbiology, 2014
Label-free bacterial colony phenotyping technology called BARDOT (BActerial Rapid Detection using Optical scattering Technology) provided successful classification of several different bacteria at the genus, species, and serovar level. Recent experiments
Huisung eKim, Atul K Singh, Arun K Bhunia, Euiwon eBae   +3 more
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Advanced modulation technology development for earth station demodulator applications [PDF]

The purpose of this contract was to develop a high rate (200 Mbps), bandwidth efficient, modulation format using low cost hardware, in 1990's technology. The modulation format chosen is 16-ary continuous phase frequency shift keying (CPFSK).
Crowley, R. D., Davis, R. C., Gann, J. A., Roesch, J. F., Wernlund, J. V., Wright, T.   +5 more
core   +1 more source