Results 111 to 120 of about 786,843 (253)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Improving radar performance with constant envelope multi-level chirp

Tehnički Glasnik, 2019
M-level Continuous Phase Chirp Modulation is considered for data transmission. In this article, we would like to propose a new approach to transmitting information with the help of multi-level wave guide signaling. The main problem with the classic chirp
Farhad Bahadori-Jahromi, Alireza Hassannejad   +1 more
doaj   +1 more source

On linear structure and phase rotation invariant properties of block 2(sup l)-PSK modulation codes [PDF]

Two important structural properties of block 2(l)-ary PSK (phase shift keying) modulation codes, linear structure and phase symmetry, are investigated.
Lin, Shu
core   +1 more source

The dressed atom as binary phase modulator: towards attojoule/edge optical phase-shift keying

, 2010
Nanophotonic technologies offer great promise for ultra-low power optical signal processing, but relatively few nonlinear-optical phenomena have yet been explored as bases for robust digital modulation/switching~\cite{Yang07,Fara08,Liu10,Noza10}. Here we
Alsing, Armen, Dmitri S. Pavlichin, Drever, Faraon, Faraon, Hideo Mabuchi, Jaynes, Joseph Kerckhoff, Liu, Mabuchi, Mabuchi, Michael A. Armen, Nozaki, Tan, Viterbi, Yang   +16 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Flexible digital modulation and coding synthesis for satellite communications [PDF]

An architecture and a hardware prototype of a flexible trellis modem/codec (FTMC) transmitter are presented. The theory of operation is built upon a pragmatic approach to trellis-coded modulation that emphasizes power and spectral efficiency.
Budinger, James, Hoerig, Craig, Tague, John, Vanderaar, Mark   +3 more
core   +1 more source

Uniform cross phase modulation for nonclassical radiation pulses

, 2010
We propose a scheme to achieve a uniform cross phase modulation (XPM) for two nonclassical light pulses and study its application for quantum non-demolition measurements of the photon number in a pulse and for controlled phase gates in quantum ...
Abbou, Bajcsy, Bajcsy, Barry C. Sanders, Boivin, Boller, Chang, Chiang, Chuang, Gehring, Harris, Harris, Hau, Joneckis, Kang, Karl-Peter Marzlin, Knill, Koshino, Lindblad, Londero, Lukin, Lukin, Matsko, Munro, Nemoto, Ottaviani, Petrosyan, Petrosyan, Rebic, Rebic, Renn, Rothenberg, Sanaka, Sanders, Sanders, Schmidt, Sergey A. Moiseev, Shapiro, Shapiro, Shapiro, Tyc, Wang, Wootters, Zeng-Bin Wang   +43 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Multi-mode single sideband time modulation harmonic adaptive beamforming

Zhongguo Jianchuan Yanjiu
ObjectiveThis study proposes an innovative beamforming method to achieve high-efficiency harmonic adaptive beamforming through multi-mode single sideband time modulation technology.MethodA multi-mode single sideband time modulation module containing ...
Tao YANG, Xiaonan ZHAO, Zhenji LIU, Tingting FAN, Liu YANG, Yu XIA, Jingfeng CHEN   +6 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source