Results 101 to 110 of about 5,106,399 (296)
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Fresnel Field Phase Retrieval via High-speed Phase Modulation
工程科学与技术, 2022 The multi-intensity phase retrieval methods obtain different coded diffraction patterns by changing the physical parameters in the optical imaging system, which can achieve the best convergence of phase and high-precision reconstruction without ...
Cheng ZHANG +4 more
doaj
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Three-Dimensional EXIT Chart Analysis of Iterative Detection Aided Coded Modulation Schemes
, 2006 The iterative convergence of iteratively detected coded modulation schemes having different block lengths, decoding complexity and an unequal error protection capability is studied, when communicating over AWGNchannels using 8PSK modulation.
Ng, S.X., Tee, R.Y.S., Hanzo, L.
core +1 more source
High-Frequency Modulation Spectroscopy with a THz Quantum-Cascade Laser [PDF]
, 2013 A terahertz absorption spectrometer with a quantum-cascade laser (QCL) for high-resolution molecular spectroscopy is realized. The spectrometer is based on highfrequency (up to 50 MHz) modulation of the QCL frequency.
H.-W. Hubers +11 more
core +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Near-capacity turbo trellis coded modulation design based on EXIT charts and union bounds
, 2008 Bandwidth efficient parallel-concatenated Turbo Trellis Coded Modulation (TTCM) schemes were designed for communicating over uncorrelated Rayleigh fading channels.
Alamri, Osamah +4 more
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source