Results 111 to 120 of about 36,496 (304)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Enhanced Graphene Based Electronically Tunable Phase Shifter. [PDF]
Micromachines (Basel), 2023 Yasir M, Peinetti F, Savi P.
europepmc +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Double reference pulsed phase locked loop [PDF]
, 1986 A double reference pulse phase locked loop is described which measures the phase shift between tone burst signals initially derived from the same periodic signal source (voltage controlled oscillator) and delayed by different amounts because of two ...
Heyman, J. S.
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Analysis and Design of Wideband 90° Microstrip Hybrid Coupler
IEEE Access, 2019 A wideband 90° microstrip hybrid coupler with a bandwidth of 84.3% is proposed. The hybrid coupler consists of a two-section coupled-line power divider and a 90° phase shifter.
Ruying Sun +3 more
doaj +1 more source
Compact broadband electronically controllable SIW phase shifter for 5G phased array antennas
, 2018 This work presents a novel compact and broadband electronically controllable substrate integrated waveguide (SIW) phase shifter intended for beamsteering applications in antenna arrays for 5G wireless communication. The proposed phase shifter is designed
Doychinov, V, Malik, BT, Robertson, ID
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Optimizations of Double Titanium Nitride Thermo-Optic Phase-Shifter Heaters Using SOI Technology. [PDF]
Sensors (Basel), 2023 Krause EE, Malka D.
europepmc +1 more source