Results 131 to 140 of about 87,708 (328)

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Corrigendum: Modeling a delayed phase transition in the early Universe (2014J. Phys. G: Nucl. Part. Phys.41125005) [PDF]

, 2015
Daniel Yueker, I. N. Mishustin, Marcus Bleicher   +2 more
openalex   +1 more source

Baryon number creation and phase transitions in the early universe

, 1982
Piet Hut, F. R. Klinkhamer
openalex   +3 more sources

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

First Order Phase Transitions as a Source of Black Holes in the Early\n Universe [PDF]

, 1999
Maxim Khlopov, R. Konoplich, S. G. Rubin, A. Sakharov   +3 more
openalex   +1 more source

Generalized inflation and confinement phase transitions in the early universe

Zeitschrift f�r Physik C Particles and Fields, 1989
Giving up the restriction e/p=const, we show that equations of state with e−3p=Δ>0 will be driven to the inflationary solution with e=−p after sufficiently long times. Subsequently, we show that confinement transitions may provide such an equation of state due to a change of degrees of freedom.
openaire   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

The discriminant power of bubble wall velocities: gravitational waves and electroweak baryogenesis

Journal of High Energy Physics
A precise determination of the bubble wall velocity v w is crucial for making accurate predictions of the baryon asymmetry and gravitational wave (GW) signals in models of electroweak baryogenesis (EWBG).
Marcela Carena, Aurora Ireland, Tong Ou, Isaac R. Wang   +3 more
doaj   +1 more source