Results 131 to 140 of about 88,270 (291)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

A model for inflaton induced baryogenesis and its phenomenological consequences

Journal of High Energy Physics
In this study, we introduce a novel approach aimed at addressing the longstanding baryon-anti-baryon asymmetry conundrum. Our proposed mechanism suggests that baryon numbers were generated during the inflationary epoch through the dynamics of the ...
Haipeng An, Qi Chen, Yuan Yin
doaj   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Implications of phase transitions in the early universe

, 1984
Imperial Users ...
Bhattacharjee, P., Bhattacharjee, P.
openaire   +1 more source

Anisotropic to Isotropic Phase Transitions in the Early Universe

, 2012
We propose that the early Universe was not Lorentz symmetric and that a gradual transition to the Lorentz symmetric phase occurred. An underlying form of the Dirac equation hints to such a transition for fermions. Fermions were coupled to space-time in a non-trivial manner such that they were massless in the Lorentz violating phase.
openaire   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Phase transitions in the early Universe: Impacts on BBN and CMB observables

Physical Review D
We explore the effects of low-scale cosmological first-order phase transitions (PTs) on big bang nucleosynthesis (BBN) and cosmic microwave background (CMB) anisotropies and distortions. We examine two scenarios: the PT energy acts as additional background energy, modifying the expansion history; and serves as energy injection into the baryon-photon ...
Rui Xu, Jiachen Lu, Shihao Deng, Ligong Bian   +3 more
openaire   +2 more sources

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

The discriminant power of bubble wall velocities: gravitational waves and electroweak baryogenesis

Journal of High Energy Physics
A precise determination of the bubble wall velocity v w is crucial for making accurate predictions of the baryon asymmetry and gravitational wave (GW) signals in models of electroweak baryogenesis (EWBG).
Marcela Carena, Aurora Ireland, Tong Ou, Isaac R. Wang   +3 more
doaj   +1 more source