Results 141 to 150 of about 87,708 (328)

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

A model for inflaton induced baryogenesis and its phenomenological consequences

Journal of High Energy Physics
In this study, we introduce a novel approach aimed at addressing the longstanding baryon-anti-baryon asymmetry conundrum. Our proposed mechanism suggests that baryon numbers were generated during the inflationary epoch through the dynamics of the ...
Haipeng An, Qi Chen, Yuan Yin
doaj   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Primordial black holes as dark matter: interferometric tests of phase transition origin

Journal of High Energy Physics
We show that primordial black holes — in the observationally allowed mass window with f PBH = 1 — formed from late nucleating patches in a first order phase transition imply upcoming gravitational wave interferometers will see a large stochastic ...
Iason Baldes, María Olalla Olea-Romacho
doaj   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Gravitational waves from phase transitions and cosmic strings in neutrino mass models with multiple majorons

Journal of High Energy Physics
We explore the origin of Majorana masses within the majoron model and how this can lead to the generation of a distinguishable primordial stochastic background of gravitational waves.
Pasquale Di Bari, Stephen F. King, Moinul Hossain Rahat   +2 more
doaj   +1 more source

Phase Transition in the Early Universe and Charge Quantisation

, 1995
It is shown, for the first time , that surprisingly the electric charge loses all physical meaning above the electro-weak phase transition temperature. Implications of this discovery in the context of the early universe within the framework of various unified models are discussed.
openaire   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Initial conditions for GRMHD simulations of electroweak and QCD phase transitions in the early Universe

, 2023
J. M. Barrera, Aleisha Warren, David Garrison   +2 more
openalex   +1 more source

Spontaneous symmetry breaking in the late Universe and glimpses of early Universe phase transitions à la baryogenesis [PDF]

, 2021
Мухаммед Сами, Radouane Gannouji   +1 more
openalex   +1 more source