Results 141 to 150 of about 84,152 (313)

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

Breast Cancer and Aging: Understanding the Complex Relationship and Implications for Prevention and Screening

open access: yesAging and Cancer, EarlyView.
ABSTRACT Background Breast cancer is a multifactorial disease that affects many women worldwide. Age is the most important risk factor for breast cancer, with an increased incidence markedly after the age of 50. The relationships of aging to breast cancer have been thoroughly examined, and notable connections regarding various age‐related changes in ...
Mehran Radak   +3 more
wiley   +1 more source

Non-thermal production of heavy vector dark matter from relativistic bubble walls

open access: yesJournal of High Energy Physics
Heavy vector boson dark matter at the TeV scale or higher may be produced non-thermally in a first-order phase transition taking place at a lower energy scale.
Wen-Yuan Ai   +3 more
doaj   +1 more source

Leveraging Artificial Intelligence in Research and Scholarly Work: Innovative Approaches and Practical Applications

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT This article explores how artificial intelligence (AI) is reshaping scholarly research and writing for faculty in higher education. As AI becomes increasingly integrated into academic workflows, it offers opportunities to enhance efficiency, exchange ideas, and foster creativity, while also raising critical questions about authorship ...
Adam L. McClain, Scott Barton
wiley   +1 more source

Phase Transitions in the Early Universe [PDF]

open access: green, 2011
W-Y. P. Hwang, Sang Pyo Kim
openalex   +1 more source

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