Results 81 to 90 of about 266 (95)

Understanding prokaryotic adaptation through advanced DNA methylation detection techniques. [PDF]

ISME J
Chen Z, Ong CT, Ross EM.
europepmc   +1 more source

Genetic variation regulates the activation and specificity of Restriction-Modification systems in Neisseria gonorrhoeae. [PDF]

Sci Rep, 2019
Sánchez-Busó L, Golparian D, Parkhill J, Unemo M, Harris SR.   +4 more
europepmc   +1 more source

The HMW2 adhesin of non-typeable Haemophilus influenzae is a human-adapted lectin that mediates high-affinity binding to 2-6 linked N-acetylneuraminic acid glycans. [PDF]

Biochem Biophys Res Commun, 2018
Atack JM, Day CJ, Poole J, Brockman KL, Bakaletz LO, Barenkamp SJ, Jennings MP.   +6 more
europepmc   +1 more source

Complete Genome Sequence of Moraxella catarrhalis Strain CCRI-195ME, Isolated from the Middle Ear. [PDF]

Genome Announc, 2017
Tan A, Blakeway LV, Bakaletz LO, Boitano M, Clark TA, Korlach J, Jennings MP, Peak IR, Seib KL.   +8 more
europepmc   +1 more source

Phase variation of a Type IIG restriction-modification enzyme alters site-specific methylation patterns and gene expression in Campylobacter jejuni strain NCTC11168. [PDF]

Nucleic Acids Res, 2016
Anjum A, Brathwaite KJ, Aidley J, Connerton PL, Cummings NJ, Parkhill J, Connerton I, Bayliss CD.   +7 more
europepmc   +1 more source

A biphasic epigenetic switch controls immunoevasion, virulence and niche adaptation in non-typeable Haemophilus influenzae. [PDF]

Nat Commun, 2015
Atack JM, Srikhanta YN, Fox KL, Jurcisek JA, Brockman KL, Clark TA, Boitano M, Power PM, Jen FE, McEwan AG, Grimmond SM, Smith AL, Barenkamp SJ, Korlach J, Bakaletz LO, Jennings MP.   +15 more
europepmc   +1 more source

Exploiting haem-iron dependence of nontypeable <i>Haemophilus influenzae</i>: an avenue for future therapeutic development. [PDF]

Front Cell Infect Microbiol
Atto B, Gell DA, Marsh R, Tristram S.
europepmc   +1 more source

The phasevarion: A genetic system controlling coordinated, random switching of expression of multiple genes [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 2005
Several host-adapted bacterial pathogens contain methyltransferases associated with type III restriction-modification (R-M) systems that are subject to reversible, high-frequency on/off switching of expression (phase variation). To investigate the role of phase-variable expression of R-M systems, we made a mutant strain lacking the
Michael P Jennings, Katryn Stacey, Yogitha Srikhanta   +2 more
exaly   +9 more sources

The phasevarion: phase variation of type III DNA methyltransferases controls coordinated switching in multiple genes [PDF]

Nature Reviews Microbiology, 2010
In several host-adapted pathogens, phase variation has been found to occur in genes that encode methyltransferases associated with type III restriction-modification systems. It was recently shown that in the human pathogens Haemophilus influenzae, Neisseria gonorrhoeae and Neisseria meningitidis phase variation of a type III DNA methyltransferase ...
Michael P Jennings, Yogitha Srikhanta, Jennings Michael P   +2 more
exaly   +8 more sources

Epigenetic Regulation of Virulence and Immunoevasion by Phase-Variable Restriction-Modification Systems in Bacterial Pathogens [PDF]

Annual Review of Microbiology, 2020
Human-adapted bacterial pathogens use a mechanism called phase variation to randomly switch the expression of individual genes to generate a phenotypically diverse population to adapt to challenges within and between human hosts.
Michael P Jennings, Kate Seib, Yogitha Srikhanta   +2 more
exaly   +3 more sources