Results 71 to 80 of about 189 (85)

A survey of Type III restriction-modification systems reveals numerous, novel epigenetic regulators controlling phase-variable regulons; phasevarions. [PDF]

Nucleic Acids Res, 2018
Atack JM, Yang Y, Seib KL, Zhou Y, Jennings MP.   +4 more
europepmc   +1 more source

Phase-variable restriction/modification systems are required for Helicobacter pylori colonization. [PDF]

Gut Pathog, 2014
Gauntlett JC, Nilsson HO, Fulurija A, Marshall BJ, Benghezal M.   +4 more
europepmc   +1 more source

Genetic variation regulates the activation and specificity of Restriction-Modification systems in Neisseria gonorrhoeae. [PDF]

Sci Rep, 2019
Sánchez-Busó L, Golparian D, Parkhill J, Unemo M, Harris SR.   +4 more
europepmc   +1 more source

The HMW2 adhesin of non-typeable Haemophilus influenzae is a human-adapted lectin that mediates high-affinity binding to 2-6 linked N-acetylneuraminic acid glycans. [PDF]

Biochem Biophys Res Commun, 2018
Atack JM, Day CJ, Poole J, Brockman KL, Bakaletz LO, Barenkamp SJ, Jennings MP.   +6 more
europepmc   +1 more source

Complete Genome Sequence of Moraxella catarrhalis Strain CCRI-195ME, Isolated from the Middle Ear. [PDF]

Genome Announc, 2017
Tan A, Blakeway LV, Bakaletz LO, Boitano M, Clark TA, Korlach J, Jennings MP, Peak IR, Seib KL.   +8 more
europepmc   +1 more source

Phase variation of a Type IIG restriction-modification enzyme alters site-specific methylation patterns and gene expression in Campylobacter jejuni strain NCTC11168. [PDF]

Nucleic Acids Res, 2016
Anjum A, Brathwaite KJ, Aidley J, Connerton PL, Cummings NJ, Parkhill J, Connerton I, Bayliss CD.   +7 more
europepmc   +1 more source

A biphasic epigenetic switch controls immunoevasion, virulence and niche adaptation in non-typeable Haemophilus influenzae. [PDF]

Nat Commun, 2015
Atack JM, Srikhanta YN, Fox KL, Jurcisek JA, Brockman KL, Clark TA, Boitano M, Power PM, Jen FE, McEwan AG, Grimmond SM, Smith AL, Barenkamp SJ, Korlach J, Bakaletz LO, Jennings MP.   +15 more
europepmc   +1 more source

Exploiting haem-iron dependence of nontypeable <i>Haemophilus influenzae</i>: an avenue for future therapeutic development. [PDF]

Front Cell Infect Microbiol
Atto B, Gell DA, Marsh R, Tristram S.
europepmc   +1 more source

The phasevarion: phase variation of type III DNA methyltransferases controls coordinated switching in multiple genes

Nature Reviews Microbiology, 2010
In several host-adapted pathogens, phase variation has been found to occur in genes that encode methyltransferases associated with type III restriction-modification systems.
Michael P Jennings, Yogitha Srikhanta
exaly   +2 more sources

Epigenetic Regulation of Virulence and Immunoevasion by Phase-Variable Restriction-Modification Systems in Bacterial Pathogens

Annual Review of Microbiology, 2020
Human-adapted bacterial pathogens use a mechanism called phase variation to randomly switch the expression of individual genes to generate a phenotypically diverse population to adapt to challenges within and between human hosts.
Michael P Jennings, Kate Seib, Yogitha Srikhanta   +2 more
exaly   +2 more sources